Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRD | O14764 | 1/20 | 0.65 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.65 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.65 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.65 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.65 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.65 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.65 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | PKM | P14618 | 2/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MGLL | Q99685 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15473398 | 0.88 | GABRD (0.63) | GABRDGABRA1GABRB1GABRA5GABRA3 | |
| SCHEMBL4557193 | 0.85 | ALDH1A1 (0.84) | GABRDGABRA1GABRB1GABRA5GABRA3 | |
| SCHEMBL10726712 | 0.85 | ALDH1A1 (0.84) | GABRDGABRA1GABRB1GABRA5GABRA3 | |
| SCHEMBL12082834 | 0.84 | GABRD (0.63) | GABRDGABRA1GABRB1GABRA5GABRA3 | |
| SCHEMBL17572990 | 0.82 | GABRD (0.57) | GABRDGABRA1GABRB1GABRA5GABRA3 | |
| SCHEMBL12606631 | 0.82 | ALDH1A1 (0.62) | ALDH1A1HPGDKMT2AMAPTLMNA | |
| SCHEMBL25332380 | 0.81 | GABRD (0.60) | GABRDGABRA1GABRB1GABRA5GABRA3 | |
| SCHEMBL1753628 | 0.81 | HPGD (0.76) | ALDH1A1PKMHPGDMEN1KMT2A | |
| SCHEMBL10192065 | 0.81 | ALDH1A1 (0.71) | GABRDGABRA1GABRB1GABRA5GABRA3 | |
| SCHEMBL14297349 | 0.81 | PKM (0.61) | GABRDGABRA1GABRB1GABRA5GABRA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110124867-A1 | Process and intermediates for the Synthesis of heterocyclic Substituted Piperazines with CXCR3 Antagonist Activity | SCHERING CORPORATION (US) | 2011-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110124867-A1 | Process and intermediates for the Synthesis of heterocyclic Substituted Piperazines with CXCR3 Antagonist Activity | CXCR3, CXCR5, CCR5 | GABRD 1231/4885GABRA1 1053/4885GABRB1 1423/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.