Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 6/20 | 0.77 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19484293 | 1.00 | VDR (0.77) | VDRCYP24A1 | |
| SCHEMBL9009904 | 1.00 | VDR (0.77) | VDRCYP24A1 | |
| Dp001 SCHEMBL8303273 | 0.94 | VDR (0.81) | VDR | |
| Dp001 SCHEMBL21206294 | 0.94 | VDR (0.81) | VDR | |
| Dp001 SCHEMBL19988220 | 0.94 | VDR (0.81) | VDR | |
| Dp001 SCHEMBL15371106 | 0.94 | VDR (0.81) | VDR | |
| Dp001 SCHEMBL10307542 | 0.94 | VDR (0.81) | VDR | |
| Dp001 SCHEMBL15371114 | 0.94 | VDR (0.81) | VDR | |
| Dp001 SCHEMBL18470321 | 0.94 | VDR (0.81) | VDR | |
| Dp001 SCHEMBL12932256 | 0.94 | VDR (0.81) | VDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8349818-B2 | Method of preventing Type 1 diabetes | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2013-01-08 | — | — | US | disclosed |
| US-20110124609-A1 | Method of Preventing Type I Diabetes | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2011-05-26 | — | — | US | disclosed |
| US-20110034426-A1 | Method of Preventing Renal Disease and Treating Symptoms Thereof | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2011-02-10 | — | — | US | disclosed |
| US-7718636-B2 | Use of 2-methylene-19-nor-20(S)-1alpha,25dihydroxy vitamin d3 to inhibit mammary tumor | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2010-05-18 | — | — | US | disclosed |
| US-7214671-B2 | Administering -methylene-19-nor-20(S)-1 alpha ,25-dihydroxyvitamin D3 for prophylaxis of osteoporosis | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2007-05-08 | — | — | US | disclosed |
| US-7214670-B2 | Use of 2-methylene-19-nor-20(S)-1α,25-dihydroxyvitamin D3 to increase the life expectancy of human beings | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2007-05-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110034426-A1 | Method of Preventing Renal Disease and Treating Symptoms Thereof | CYP24A1, CYP27B1, CYP2R1 | VDR 4/4885CYP24A1 1/4885 |
| US-20110124609-A1 | Method of Preventing Type I Diabetes | CYP24A1, CYP27B1, CYP2R1 | VDR 4/4885CYP24A1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.