Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.39 |
| ▸ | HTR2B | P41595 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4441590 | 0.98 | LTA4H (0.44) | LTA4HTSHRCYP3A4TP53MAPK1 | |
| SCHEMBL329237 | 0.98 | LTA4H (0.44) | LTA4HTSHRCYP3A4TP53MAPK1 | |
| SCHEMBL339719 | 0.98 | LTA4H (0.44) | LTA4HTSHRCYP3A4TP53MAPK1 | |
| SCHEMBL5495328 | 0.98 | LTA4H (0.44) | LTA4HTSHRCYP3A4TP53MAPK1 | |
| SCHEMBL338315 | 0.98 | LTA4H (0.44) | LTA4HTSHRCYP3A4TP53MAPK1 | |
| SCHEMBL5144146 | 0.98 | LTA4H (0.44) | LTA4HTSHRCYP3A4TP53MAPK1 | |
| SCHEMBL659359 | 0.98 | LTA4H (0.44) | LTA4HTSHRCYP3A4TP53MAPK1 | |
| SCHEMBL2871187 | 0.98 | LTA4H (0.44) | LTA4HTSHRCYP3A4TP53MAPK1 | |
| SCHEMBL4943659 | 0.98 | LTA4H (0.44) | LTA4HTSHRCYP3A4TP53MAPK1 | |
| SCHEMBL1509376 | 0.98 | LTA4H (0.44) | LTA4HTSHRCYP3A4TP53MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1036 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240124419-A1 | SMALL MOLECULE INHIBITORS OF GRP78 AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2024-04-18 | — | — | US | claimed |
| EP-4288416-A2 | SMALL MOLECULE INHIBITORS OF GRP78 AND USES THEREOF | The Regents Of The University Of Michigan (US) | 2023-12-13 | — | — | EP | claimed |
| CN-116178197-A | (Z) -N-substituted enaminone derivative, preparation method and application thereof | 浙江医药股份有限公司新昌制药厂 | 2023-05-30 | — | — | CN | claimed |
| WO-2022169834-A2 | SMALL MOLECULE INHIBITORS OF GRP78 AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2022-08-11 | — | — | WO | claimed |
| CN-114206886-A | Luminescent gold (III) compound, method for preparing same, and organic light emitting device using same | 广东聚华印刷显示技术有限公司 | 2022-03-18 | — | — | CN | claimed |
| CN-114057625-A | C2-acyloxy-3-indolinone derivative and preparation method and application thereof | 五邑大学 | 2022-02-18 | — | — | CN | claimed |
| WO-2021016814-A1 | LUMINESCENT GOLD (III) COMPOUND, METHOD FOR PREPARING THE SAME, AND ORGANIC LIGHT-EMITTING DEVICE USING THE SAME | GUANGDONG JUHUA PRINTED DISPLAY TECHNOLOGY CO., LTD. (CN) | 2021-02-04 | — | — | WO | claimed |
| CN-106232120-B | Process for preparing N-benzyl-3-hydroxy-4-substituted-pyridin-2- (1H) -ones | 爱尔皮奥治疗有限公司 | 2021-01-08 | — | — | CN | claimed |
| WO-2020132459-A1 | QUINOLINYL-PYRAZINE-CARBOXAMIDE COMPOUNDS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2020-06-25 | — | — | WO | claimed |
| US-10400173-B2 | Siloxane-modified cyclotriphosphazene halogen-free flame retardant, preparation process and use thereof | SHENGYI TECHNOLOGY CO., LTD. (CN) | 2019-09-03 | — | — | US | claimed |
| US-5324788-A | A copolymer of a 4-acyloxystyrene and an acrylate modified by an alcohol to effect an ester interchange, an aminoplast crosslinking agent and solvent; enamel coatings; acid and solvent resistance; hardness; gloss; autos | EASTMAN KODAK COMPANY (US) | 1994-06-28 | — | — | US | claimed |
| EP-0294785-B1 | MAGENTA DYE-FORMING COUPLER | FUJI PHOTO FILM CO., LTD. (JP) | 1992-11-25 | — | — | EP | claimed |
| US-5116990-A | MAGENTA DYE-FORMING COUPLER | FUJI PHOTO FILM CO., LTD. (JP) | 1992-05-26 | — | — | US | claimed |
| US-5078906-A | Organic lithium-potassium complexes for metallization reactions, preparation of aspirin substitutes, fenoprofen | MINE SAFETY APPLIANCES COMPANY (US) | 1992-01-07 | — | — | US | claimed |
| EP-0379987-A2 | Process for the preparation of alpha-arylalkanoic acids | Mine Safety Appliances Company (US) | 1990-08-01 | — | — | EP | claimed |
| US-4910337-A | Process for the preparation of α-arylalkanoic acids | MINE SAFETY APPLIANCES COMPANY (US) | 1990-03-20 | — | — | US | claimed |
| EP-0342804-A2 | Trioxane composition and insect-proofing agent | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1989-11-23 | — | — | EP | claimed |
| WO-1989010365-A1 | PYRAZOLOPYRIDINE TYPE MEVALONOLACTONES | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1989-11-02 | — | — | WO | claimed |
| US-H533-H | 1H-PYRAZOLO(1,5-B)OR(5,1-C)-1,2,4-TRIAZOLE MAGENTA COUPLER | FUJI PHOTO FILM CO., LTD. (JP) | 1988-10-04 | — | — | US | claimed |
| US-3935196-A | Useful pro-drug forms of theophylline | INTERX RESEARCH CORPORATION (US) | 1976-01-27 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240124419-A1 | SMALL MOLECULE INHIBITORS OF GRP78 AND USES THEREOF | HSPA5, HSPA2, PSMG3 | LTA4H 3140/4885TSHR 4040/4885CYP3A4 3078/4885 |
| US-10400173-B2 | Siloxane-modified cyclotriphosphazene halogen-free flame retardant, preparation process and use thereof | PFAS, POLL, POLR1E | LTA4H 170/4885TSHR 863/4885CYP3A4 1345/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.