Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL717250 | 0.91 | TSHR (0.45) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL5050848 | 0.83 | TSHR (0.49) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL1264172 | 0.79 | FOLH1 (0.47) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL3263232 | 0.78 | THRB (0.47) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL8602798 | 0.77 | THRB (0.46) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL5057246 | 0.77 | TSHR (0.48) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL159197 | 0.76 | FOLH1 (0.46) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL5059000 | 0.75 | TSHR (0.51) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL1263017 | 0.75 | FOLH1 (0.49) | THRBTSHRFOLH1 | |
| SCHEMBL11177266 | 0.74 | TSHR (0.46) | THRBTSHRALDH1A1POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6583197-B1 | Excellent sustained release of fluorine; free radical polymerizable unsaturated monomer having an acid group, acid-reactive fluoroaluminsilicate glass filler, water, solvent | KABUSHIKI KAISHA SHOFU (JP) | 2003-06-24 | — | — | US | claimed |
| US-7879924-B2 | Dental composite resin cement, dental primer and dental adhesive kit containing them | KABUSHIKI KAISHA SHOFU (JP) | 2011-02-01 | — | — | US | disclosed |
| US-20090048366-A1 | Dental Composite Resin Cement, Dental Primer and Dental Adhesive Kit Containing Them | KABUSHIKI KAISHA SHOFU (JP) | 2009-02-19 | — | — | US | disclosed |
| EP-1066813-B1 | Dental adhesive composition | SHOFU KK (JP) | 2004-10-06 | — | — | EP | disclosed |
| US-6583197-B1 | Excellent sustained release of fluorine; free radical polymerizable unsaturated monomer having an acid group, acid-reactive fluoroaluminsilicate glass filler, water, solvent | KABUSHIKI KAISHA SHOFU (JP) | 2003-06-24 | — | — | US | disclosed |
| EP-1066813-A2 | Dental adhesive composition | KABUSHIKI KAISHA SHOFU (JP) | 2001-01-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090048366-A1 | Dental Composite Resin Cement, Dental Primer and Dental Adhesive Kit Containing Them | CDH1, JMJD7, WDR91 | THRB 2753/4885TSHR 4536/4885ALDH1A1 627/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.