Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.32 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.32 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3173661 | 0.90 | THRB (0.42) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL159197 | 0.82 | FOLH1 (0.46) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL3802304 | 0.81 | THRB (0.55) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL6757327 | 0.81 | TSHR (0.59) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL4313868 | 0.81 | THRB (0.55) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL23646638 | 0.80 | THRB (0.42) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL674035 | 0.80 | THRB (0.42) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL11023086 | 0.79 | THRB (0.48) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL8156029 | 0.79 | THRB (0.39) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL13559179 | 0.79 | THRB (0.52) | THRBTSHRPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100021869-A1 | (METH)ACRYLOYL-CONTAINING MATERIALS, COMPOSITIONS, AND METHODS | 3M INNOVATIVE PROPERTIES COMPANY | 2010-01-28 | — | — | US | claimed |
| EP-2114350-A1 | (METH)ACRYLOYL-CONTAINING MATERIALS, COMPOSITIONS, AND METHODS | 3M Innovative Properties Company (US) | 2009-11-11 | — | — | EP | claimed |
| WO-2008082881-A1 | (METH)ACRYLOYL-CONTAINING MATERIALS, COMPOSITIONS, AND METHODS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2008-07-10 | — | — | WO | claimed |
| US-20100021869-A1 | (METH)ACRYLOYL-CONTAINING MATERIALS, COMPOSITIONS, AND METHODS | 3M INNOVATIVE PROPERTIES COMPANY | 2010-01-28 | — | — | US | disclosed |
| EP-2114350-A1 | (METH)ACRYLOYL-CONTAINING MATERIALS, COMPOSITIONS, AND METHODS | 3M Innovative Properties Company (US) | 2009-11-11 | — | — | EP | disclosed |
| WO-2008082881-A1 | (METH)ACRYLOYL-CONTAINING MATERIALS, COMPOSITIONS, AND METHODS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2008-07-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100021869-A1 | (METH)ACRYLOYL-CONTAINING MATERIALS, COMPOSITIONS, AND METHODS | MT-CO1, PAM, MT-CO2 | THRB 804/4885TSHR 2522/4885POLB 2716/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.