Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1263018 | 0.91 | THRB (0.41) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL5059000 | 0.85 | TSHR (0.51) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL610577 | 0.77 | TSHR (0.49) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL27865298 | 0.77 | TSHR (0.49) | TSHRTHRBPOLBAPEX1HTT | |
| Phosphoric Acid SCHEMBL3464242 | 0.75 | TSHR (0.62) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL1262620 | 0.75 | TSHR (0.54) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL1263022 | 0.75 | TSHR (0.54) | TSHRTHRBPOLBAPEX1HTT | |
| Phosphoric Acid SCHEMBL17294810 | 0.74 | TSHR (0.53) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL41489 | 0.74 | TSHR (0.56) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL19405762 | 0.74 | TSHR (0.57) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3848418-B1 | DENTAL CURABLE COMPOSITION AND METHOD FOR PRODUCING DENTAL CURABLE COMPOSITION | TOKUYAMA DENTAL CORP (JP) | 2024-05-22 | — | — | EP | disclosed |
| US-20220169844-A1 | COMPOSITE PARTICLES, KIT, MATERIAL, AND METHOD FOR PRODUCING COMPOSITE PARTICLES | SUN MEDICAL CO., LTD. (JP) | 2022-06-02 | — | — | US | disclosed |
| EP-3415539-B1 | POLYMERIZABLE COMPOSITION AND KIT THEREOF, AND POLYMERIZATION INITIATOR | SUN MEDICAL CO LTD (JP) | 2022-03-30 | — | — | EP | disclosed |
| EP-3508190-B1 | LIGHT CURABLE COMPOSITION | TOKUYAMA DENTAL CORP (JP) | 2022-02-09 | — | — | EP | disclosed |
| EP-3613779-B1 | CURABLE COMPOSITION | TOKUYAMA DENTAL CORP (JP) | 2021-11-24 | — | — | EP | disclosed |
| US-20210324178-A1 | COMPOSITE MATERIAL, CURABLE COMPOSITION, AND METHOD FOR PRODUCING CURABLE COMPOSITION | TOKUYAMA DENTAL CORPORATION (JP) | 2021-10-21 | — | — | US | disclosed |
| US-11130864-B2 | Polymerizable composition and kit, and polymerization initiator | SUN MEDICAL CO., LTD. (JP) | 2021-09-28 | — | — | US | disclosed |
| US-11078303-B2 | Curable composition | TOKUYAMA DENTAL CORPORATION (JP) | 2021-08-03 | — | — | US | disclosed |
| US-11065183-B2 | Curable composition | TOKUYAMA DENTAL CORPORATION (JP) | 2021-07-20 | — | — | US | disclosed |
| EP-3848418-A1 | COMPOSITE MATERIAL, CURABLE COMPOSITION, AND METHOD FOR PRODUCING CURABLE COMPOSITION | Tokuyama Dental Corporation (JP) | 2021-07-14 | — | — | EP | disclosed |
| EP-2609940-A1 | THERAPEUTIC AGENT FOR PULMONARY EMPHYSEMA | Terumo Kabushiki Kaisha (JP) | 2013-07-03 | — | — | EP | disclosed |
| US-8158694-B2 | Single component dental composition containing silane coupling agent and acidic group containing polymerizable monomer | KABUSHIKI KAISHA SHOFU (JP) | 2012-04-17 | — | — | US | disclosed |
| US-20120053566-A1 | METHOD FOR TREATMENT OF EMPHYSEMA | TERUMO KABUSHIKI KAISHA (JP) | 2012-03-01 | — | — | US | disclosed |
| US-20120053513-A1 | METHOD FOR TREATMENT OF EMPHYSEMA | TERUMO KABUSHIKI KAISHA (JP) | 2012-03-01 | — | — | US | disclosed |
| US-20110112209-A1 | SINGLE-COMPONENT DENTAL COMPOSITION CONTAINING SILANE COUPLING AGENT AND ACIDIC GROUP-CONTAINING POLYMERIZABLE MONOMER | TANAKA HISAKI | 2011-05-12 | — | — | US | disclosed |
| US-7776936-B2 | One-pack type dental adhesive composition | KABUSHIKI KAISHA SHOFU (JP) | 2010-08-17 | — | — | US | disclosed |
| US-20100069524-A1 | Single-Component dental composition containing silane coupling agent and acidic group-containing polymerizable monomer | KABUSHIKI KAISHA SHOFU | 2010-03-18 | — | — | US | disclosed |
| US-20090076182-A1 | One-pack type dental adhesive composition | KABUSHIKI KAISHA SHOFU (JP) | 2009-03-19 | — | — | US | disclosed |
| EP-2036532-A2 | One pack type dental adhesive composition | Kabushiki Kaisha Shofu (JP) | 2009-03-18 | — | — | EP | disclosed |
| US-20090048426-A1 | POLYMERIZABLE PHOSPHONIC ACID DERIVATIVE AND ADHESIVE COMPOSITION COMPRISING THE SAME | KABUSHIKI KAISHA SHOFU (JP) | 2009-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100069524-A1 | Single-Component dental composition containing silane coupling agent and acidic group-containing polymerizable monomer | CAD, ITGA1, CIB1 | TSHR 4642/4885THRB 3699/4885POLB 3832/4885 |
| US-11130864-B2 | Polymerizable composition and kit, and polymerization initiator | KIT, MCM7, EPHA7 | TSHR 4807/4885THRB 3112/4885POLB 64/4885 |
| US-20110112209-A1 | SINGLE-COMPONENT DENTAL COMPOSITION CONTAINING SILANE COUPLING AGENT AND ACIDIC GROUP-CONTAINING POLYMERIZABLE MONOMER | CAD, ITGA1, CIB1 | TSHR 4642/4885THRB 3699/4885POLB 3832/4885 |
| US-20090076182-A1 | One-pack type dental adhesive composition | DSC1, ITGA1, CAD | TSHR 4689/4885THRB 4093/4885POLB 3491/4885 |
| US-20090048426-A1 | POLYMERIZABLE PHOSPHONIC ACID DERIVATIVE AND ADHESIVE COMPOSITION COMPRISING THE SAME | PTK2, ITGA1, ACTN1 | TSHR 3260/4885THRB 1372/4885POLB 689/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.