Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL563821 | 0.84 | KMT2A (0.47) | KMT2AALDH1A1DRD3MAPK1RPS6KA2 | |
| SCHEMBL38655243 | 0.83 | RAB9A (0.55) | KMT2AALDH1A1MAPK1RAB9ANPC1 | |
| SCHEMBL14960666 | 0.82 | KMT2A (0.50) | KMT2AALDH1A1MAPK1RPS6KA2RAB9A | |
| SCHEMBL8240062 | 0.81 | ALDH1A1 (0.51) | KMT2AALDH1A1DRD3MAPK1RPS6KA2 | |
| SCHEMBL18658571 | 0.81 | KMT2A (0.44) | KMT2AALDH1A1DRD3MAPK1RPS6KA2 | |
| SCHEMBL19985874 | 0.81 | MAOB (0.49) | RAB9A | |
| SCHEMBL22355050 | 0.79 | DRD3 (0.44) | KMT2AALDH1A1DRD3MAPK1RPS6KA2 | |
| SCHEMBL8862776 | 0.79 | TDP1 (0.48) | KMT2AALDH1A1MAPK1RAB9ANPC1 | |
| SCHEMBL8862689 | 0.79 | TDP1 (0.48) | KMT2AALDH1A1MAPK1RAB9ANPC1 | |
| SCHEMBL4482770 | 0.77 | ALDH1A1 (0.53) | KMT2AALDH1A1DRD3RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170088652-A1 | (ETHYLENE, VINYL ACETAL) COPOLYMERS AND THEIR USE IN LITHOGRAPHIC PRINTING PLATE PRECURSORS | AGFA OFFSET BV (BE) | 2017-03-30 | — | — | US | disclosed |
| US-20150148326-A1 | Monobactams | PFIZER (US) | 2015-05-28 | — | — | US | disclosed |
| US-20130252935-A1 | Monobactams | PFIZER INC. (US) | 2013-09-26 | — | — | US | disclosed |
| US-8455521-B2 | Diaminoalkane aspartic protease inhibitors | VITAE PHARMACEUTICALS, INC. (US) | 2013-06-04 | — | — | US | disclosed |
| US-20120302542-A1 | MONOBACTAMS | PFIZER INC | 2012-11-29 | — | — | US | disclosed |
| US-20110105506-A1 | Diaminoalkane aspartic protease inhibitors | VITAE PHARMACEUTICALS, INC. | 2011-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110105506-A1 | Diaminoalkane aspartic protease inhibitors | DNPEP, PEPD, ACE | KMT2A 2621/4885ALDH1A1 587/4885DRD3 4519/4885 |
| US-20130252935-A1 | Monobactams | MGAM, MGAM2, BPGM | KMT2A 608/4885ALDH1A1 1829/4885DRD3 3843/4885 |
| US-20150148326-A1 | Monobactams | MGAM, MGAM2, BPGM | KMT2A 608/4885ALDH1A1 1829/4885DRD3 3843/4885 |
| US-20120302542-A1 | MONOBACTAMS | MGAM, MGAM2, BPGM | KMT2A 608/4885ALDH1A1 1829/4885DRD3 3843/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.