Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 7/20 | 0.44 |
| ▸ | THRB | P10828 | 6/20 | 0.44 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.44 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.43 |
| ▸ | NAPEPLD | Q6IQ20 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | HTR1D | P28221 | 1/20 | 0.43 |
| ▸ | HTR1B | P28222 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 3/20 | 0.43 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.42 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.42 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.42 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.42 |
| ▸ | BRSK1 | Q8TDC3 | 1/20 | 0.42 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.42 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12668271 | 0.98 | THRA (0.43) | THRATHRBHCRTR1ITGA4NAPEPLD | |
| SCHEMBL12633106 | 0.94 | THRA (0.40) | THRATHRBHCRTR1ITGA4NAPEPLD | |
| SCHEMBL12633055 | 0.92 | ACHE (0.46) | THRATHRBHTR1AHTR1DHTR1B | |
| SCHEMBL12668273 | 0.91 | TSHR (0.41) | — | |
| SCHEMBL584884 | 0.89 | TSHR (0.47) | — | |
| SCHEMBL14449207 | 0.88 | THRA (0.46) | THRATHRBHTR1AHTR1DHTR1B | |
| SCHEMBL6843058 | 0.87 | CYP1A2 (0.48) | — | |
| SCHEMBL12633103 | 0.86 | MLNR (0.38) | HTR1A | |
| SCHEMBL8031578 | 0.84 | TERT (0.49) | — | |
| SCHEMBL12190732 | 0.84 | TERT (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7947674-B2 | Meso-substituted porphyrins | L. Molteni & C. Dei Fratelli Alitti (IT) | 2011-05-24 | — | — | US | disclosed |