Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 15/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 13/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8813400 | 1.00 | SLC6A3 (0.46) | SLC6A3SLC6A2SLC6A4MAPTMAPK1 | |
| SCHEMBL12635242 | 1.00 | SLC6A3 (0.46) | SLC6A3SLC6A2SLC6A4MAPTMAPK1 | |
| SCHEMBL12635278 | 0.98 | SLC6A3 (0.45) | SLC6A3SLC6A2SLC6A4MAPTMAPK1 | |
| SCHEMBL12635275 | 0.98 | SLC6A3 (0.45) | SLC6A3SLC6A2SLC6A4MAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL5205853 | 0.93 | SLC6A3 (0.41) | SLC6A3SLC6A2SLC6A4MAPTMAPK1 | |
| SCHEMBL4441694 | 0.82 | SLC6A3 (0.50) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL499846 | 0.82 | SLC6A3 (0.50) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL4236955 | 0.81 | SIGMAR1 (0.43) | SLC6A3SLC6A2SLC6A4CA12CA1 | |
| SCHEMBL1008559 | 0.80 | LMNA (0.55) | SLC6A3SLC6A2SLC6A4MAPTMAPK1 | |
| SCHEMBL5499957 | 0.80 | SLC6A3 (0.49) | SLC6A3SLC6A2SLC6A4MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110105488-A1 | SUBSTITUTED PYRROLIDINE AND PIPERIDINE COMPOUNDS, DERIVATIVES THEREOF, AND METHODS FOR TREATING PAIN | CHLORION PHARMA, INC. (CA) | 2011-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110105488-A1 | SUBSTITUTED PYRROLIDINE AND PIPERIDINE COMPOUNDS, DERIVATIVES THEREOF, AND METHODS FOR TREATING PAIN | PAM, PNN, NOD1 | SLC6A3 3089/4885SLC6A2 3841/4885SLC6A4 1945/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.