Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSPO | P30536 | 1/20 | 0.41 |
| ▸ | PTPRC | P08575 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | METAP2 | P50579 | 2/20 | 0.37 |
| ▸ | HTR7 | P34969 | 3/20 | 0.36 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | ICMT | O60725 | 4/20 | 0.35 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.34 |
| ▸ | OXTR | P30559 | 1/20 | 0.34 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12635743 | 0.73 | HTR1D (0.39) | HTR7KDM4EAPOBEC3AAPOBEC3G | |
| SCHEMBL2020983 | 0.72 | LMNA (0.50) | TSPOABL1 | |
| SCHEMBL16120015 | 0.68 | TSPO (0.67) | TSPOKDM4E | |
| SCHEMBL20209184 | 0.67 | CASP3 (0.44) | KDM4E | |
| SCHEMBL12634882 | 0.67 | KDM4E (0.34) | KDM4EAPOBEC3AAPOBEC3G | |
| Iodide SCHEMBL21196460 | 0.67 | CASP3 (0.44) | KDM4E | |
| SCHEMBL20209590 | 0.65 | MAPT (0.43) | KDM4EAPOBEC3AAPOBEC3G | |
| SCHEMBL11673547 | 0.65 | NAAA (0.50) | PTPRCPTPN1HTR7 | |
| SCHEMBL26659934 | 0.65 | FYN (0.56) | PTPRCPTPN1HTR7KDM4EAVPR2 | |
| SCHEMBL12636335 | 0.65 | APOBEC3A (0.39) | KDM4EAPOBEC3AAPOBEC3G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011079087-A1 | ENAC BLOCKERS | GLAXO GROUP LIMITED (GB) | 2011-06-30 | — | — | WO | disclosed |