Known targets — ChEMBL curated mechanism
GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHMGCRMMP1MMP13MMP7MMP8PTGS1PTGS2ileSpolrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1262562 | 0.97 | MEN1 (0.50) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL15363613 | 0.78 | ALDH1A1 (0.51) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL9063018 | 0.73 | ALDH1A1 (0.76) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL472502 | 0.70 | ALDH1A1 (0.70) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL10785663 | 0.69 | ALDH1A1 (0.31) | ALDH1A1MAPT | |
| SCHEMBL1263811 | 0.69 | ALDH1A1 (0.68) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL1262566 | 0.69 | ALDH1A1 (0.68) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL2580220 | 0.68 | ALDH1A1 (0.67) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL3272912 | 0.67 | ALDH1A1 (1.00) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL572791 | 0.66 | ALDH1A1 (0.64) | MEN1KMT2AKDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7879924-B2 | Dental composite resin cement, dental primer and dental adhesive kit containing them | KABUSHIKI KAISHA SHOFU (JP) | 2011-02-01 | — | — | US | disclosed |
| US-20090048366-A1 | Dental Composite Resin Cement, Dental Primer and Dental Adhesive Kit Containing Them | KABUSHIKI KAISHA SHOFU (JP) | 2009-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090048366-A1 | Dental Composite Resin Cement, Dental Primer and Dental Adhesive Kit Containing Them | CDH1, JMJD7, WDR91 | MEN1 2893/4885KMT2A 224/4885KDM4E 544/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.