Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 9/20 | 0.58 |
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.53 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.53 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29755942 | 1.00 | NISCH (0.58) | NISCHMAOBLMNASMN1; SMN2ADRA2A | |
| Hydrochloric Acid SCHEMBL2491030 | 0.98 | NISCH (0.56) | NISCHMAOBLMNASMN1; SMN2ADRA2A | |
| SCHEMBL8188936 | 0.93 | NISCH (0.58) | NISCHMAOBLMNASMN1; SMN2ADRA2A | |
| SCHEMBL3858563 | 0.91 | NISCH (0.55) | NISCHMAOBLMNASMN1; SMN2ADRA2A | |
| SCHEMBL12870242 | 0.84 | ACHE (0.77) | LMNASMN1; SMN2ACHE | |
| Hydrochloric Acid SCHEMBL1143150 | 0.83 | ACHE (0.76) | LMNASMN1; SMN2ACHE | |
| SCHEMBL771657 | 0.81 | NISCH (0.56) | NISCHLMNA | |
| SCHEMBL9189709 | 0.80 | NISCH (0.85) | NISCHMAOBACHE | |
| SCHEMBL16204314 | 0.79 | ACHE (0.77) | LMNASMN1; SMN2ACHE | |
| Hydrochloric Acid SCHEMBL7738650 | 0.79 | ADRA2A (0.53) | NISCHMAOBLMNASMN1; SMN2ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116813551-A | Preparation method of imidazole phenylurea dipropionate | 齐鲁晟华制药有限公司 | 2023-09-29 | — | — | CN | claimed |
| CN-116621781-A | Preparation method of 2- (3-nitrophenyl) -4, 5-dihydro-1H-imidazoline | 济南鸿湾生物技术有限公司 | 2023-08-22 | — | — | CN | claimed |
| CN-114773270-A | Production and preparation method of imidocarb dipropionate | 山东省药学科学院 | 2022-07-22 | — | — | CN | claimed |
| CN-111574455-A | Preparation method of imidocarb dipropionate and intermediate thereof | 山东省药学科学院 | 2020-08-25 | — | — | CN | claimed |
| CN-117466818-B | Method for preparing 2-aryl imidazoline compounds by solvent-free method | 潍坊弘润新材料有限公司 | 2024-04-26 | — | — | CN | disclosed |
| CN-114671810-B | Preparation method of imidazole phenylurea | 济南鸿湾生物技术有限公司 | 2024-03-22 | — | — | CN | disclosed |
| CN-117720469-A | Preparation method and application of asymmetric urea micromolecule compound and derivative | 西南大学 | 2024-03-19 | — | — | CN | disclosed |
| CN-117466818-A | Method for preparing 2-aryl imidazoline compounds by solvent-free method | 潍坊弘润新材料有限公司 | 2024-01-30 | — | — | CN | disclosed |
| CN-116813551-A | Preparation method of imidazole phenylurea dipropionate | 齐鲁晟华制药有限公司 | 2023-09-29 | — | — | CN | disclosed |
| CN-116621781-A | Preparation method of 2- (3-nitrophenyl) -4, 5-dihydro-1H-imidazoline | 济南鸿湾生物技术有限公司 | 2023-08-22 | — | — | CN | disclosed |
| CN-116621781-A | Preparation method of 2- (3-nitrophenyl) -4, 5-dihydro-1H-imidazoline | 济南鸿湾生物技术有限公司 | 2023-08-22 | — | — | CN | disclosed |
| CN-116621781-A | Preparation method of 2- (3-nitrophenyl) -4, 5-dihydro-1H-imidazoline | 济南鸿湾生物技术有限公司 | 2023-08-22 | — | — | CN | disclosed |
| CN-103896843-A | Preparation method of imidocarb | SHANDONG JIULONG FINE CHEMICAL CO LTD | 2014-07-02 | — | — | CN | disclosed |
| CN-102924380-A | Preparation method of imidocarb | QILU ANIMAL HEALTH PRODUCTS CO | 2013-02-13 | — | — | CN | disclosed |
| EP-2327677-A1 | Mono-nitration of aromatic compounds | F. Hoffmann-La Roche AG (CH) | 2011-06-01 | — | — | EP | disclosed |
| US-7429589-B2 | Mono-nitration of aromatic compounds via nitrate salts | HOFFMANN-LA ROCHE INC. (US) | 2008-09-30 | — | — | US | disclosed |
| US-7429589-B2 | Mono-nitration of aromatic compounds via nitrate salts | HOFFMANN-LA ROCHE INC. (US) | 2008-09-30 | — | — | US | disclosed |
| WO-2007125034-A2 | MONO-NITRATION OF AROMATIC COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2007-11-08 | — | — | WO | disclosed |
| US-20070255057-A1 | Mono-nitration of aromatic compounds via nitrate salts | CEDILOTE MIALL | 2007-11-01 | — | — | US | disclosed |
| US-20070255057-A1 | Mono-nitration of aromatic compounds via nitrate salts | CEDILOTE MIALL | 2007-11-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070255057-A1 | Mono-nitration of aromatic compounds via nitrate salts | NOS2, NOS3, NOS1 | NISCH 20/4885MAOB 29/4885LMNA 3223/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.