Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 2/20 | 0.69 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | TBXAS1 | P24557 | 5/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL126545 | 1.00 | AKR1C3 (0.69) | AKR1C3MAPTKMT2ANPSR1MEN1 | |
| SCHEMBL4216116 | 1.00 | AKR1C3 (0.69) | AKR1C3MAPTKMT2ANPSR1MEN1 | |
| SCHEMBL4805932 | 0.94 | AKR1C3 (0.62) | AKR1C3MAPTKMT2ANPSR1MEN1 | |
| SCHEMBL2462983 | 0.91 | AKR1C3 (0.82) | AKR1C3TBXAS1APEX1POLBTDP1 | |
| SCHEMBL2462984 | 0.91 | AKR1C3 (0.82) | AKR1C3TBXAS1APEX1POLBTDP1 | |
| SCHEMBL502895 | 0.88 | AKR1C3 (0.53) | AKR1C3MAPTKMT2ANPSR1MEN1 | |
| SCHEMBL502894 | 0.88 | AKR1C3 (0.53) | AKR1C3MAPTKMT2ANPSR1MEN1 | |
| SCHEMBL2732933 | 0.84 | AKR1C3 (0.72) | AKR1C3KMT2AMEN1TBXAS1APEX1 | |
| SCHEMBL3414243 | 0.84 | AKR1C3 (0.72) | AKR1C3KMT2AMEN1TBXAS1APEX1 | |
| SCHEMBL83882 | 0.83 | AKR1C3 (0.69) | AKR1C3KMT2AMEN1TBXAS1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 166 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4306780-A | Highly refractive copolymer of an ethylinically unsaturated alkylene oxide of bis-phenol-A and an ethylinically unsaturated aromatic compound for lens and a lens prepared therefrom | HOYA LENS CORPORATION (JP) | 1981-12-22 | — | — | US | claimed |
| EP-3910715-B1 | ADHESIVE ELECTROLYTE | TESA SE (DE) | 2025-07-09 | — | — | EP | disclosed |
| US-20250034121-A1 | COMPOUNDS AND THEIR USES AS GPR183 INHIBITORS | NANJING IMMUNOPHAGE BIOMEDICAL CO., LTD. (CN) | 2025-01-30 | — | — | US | disclosed |
| EP-4419511-A1 | COMPOUNDS AND THEIR USES AS GPR183 INHIBITORS | Nanjing Immunophage Biotech Co., Ltd (CN) | 2024-08-28 | — | — | EP | disclosed |
| CN-118201911-A | Compounds and their use as GPR183 inhibitors | 南京艾美斐生物医药科技有限公司 | 2024-06-14 | — | — | CN | disclosed |
| WO-2023066190-A1 | COMPOUNDS AND THEIR USES AS GPR183 INHIBITORS | NANJING IMMUNOPHAGE BIOTECH CO., LTD (CN) | 2023-04-27 | — | — | WO | disclosed |
| WO-2023066190-A1 | COMPOUNDS AND THEIR USES AS GPR183 INHIBITORS | NANJING IMMUNOPHAGE BIOTECH CO., LTD (CN) | 2023-04-27 | — | — | WO | disclosed |
| EP-3910715-A1 | ADHESIVE ELECTROLYTE | tesa SE (DE) | 2021-11-17 | — | — | EP | disclosed |
| EP-1952184-B1 | PHOTOCHROMIC MULTIFOCAL OPTICAL ARTICLE | TRANSITIONS OPTICAL INC (US) | 2021-08-11 | — | — | EP | disclosed |
| EP-2531889-B1 | USE OF A PHOTOPOLYMER FORMULATION WITH ESTER-BASED WRITING MONOMERS FOR THE FABRICATION OF HOLOGRAPHIC MEDIA | COVESTRO DEUTSCHLAND AG (DE) | 2020-06-03 | — | — | EP | disclosed |
| WO-2001040339-A1 | BLOCK COPOLYMERS AND METHOD FOR THE PRODUCTION AND UTILIZATION THEREOF | ROHMAX ADDITIVES GMBH (DE) | 2001-06-07 | — | — | WO | disclosed |
| WO-2001040334-A1 | COPOLYMERS WHICH CAN BE OBTAINED USING ATRP METHODS, AND METHOD FOR PRODUCING AND USING THE SAME | ROHMAX ADDITIVES GMBH (DE) | 2001-06-07 | — | — | WO | disclosed |
| WO-2001040333-A1 | GRADIENT COPOLYMERS AND METHOD FOR THE PRODUCTION THEREOF AND THEIR USE | ROHMAX ADDITIVES GMBH (DE) | 2001-06-07 | — | — | WO | disclosed |
| EP-0965619-A1 | Low odor, cold curable, (Meth)acylate reactive resin for floor coating, such réactive resin and the process for producing such floorcoating | RÖHM GMBH (DE) | 1999-12-22 | — | — | EP | disclosed |
| EP-0841380-B1 | Method of making polymeric binders and use thereof in antifouling paints | WITCO GMBH (DE) | 1999-08-25 | — | — | EP | disclosed |
| EP-0841380-A1 | Method of making polymeric binders and use thereof in antifouling paints | Witco GmbH (DE) | 1998-05-13 | — | — | EP | disclosed |
| EP-0595995-B1 | ARYLAMIDOALKYL- AND ARYLAMINOALKYL-N-HYDROXYUREA COMPOUNDS AND -N-HYDROXYFORMAMIDE DERIVATIVES HAVING LIPOXYGENASE INHIBITORY ACTIVITY | ABBOTT LAB (US) | 1997-01-15 | — | — | EP | disclosed |
| US-5514702-A | Arylamidoalkyl-N-hydroxyurea compounds having lipoxygenase inhibitory activity | ABBOTT LABORATORIES (US) | 1996-05-07 | — | — | US | disclosed |
| US-4731370-A | VASODILATOR, ANTICOAGULANT | TOYAMA CHEMICAL CO., LTD. (JP) | 1988-03-15 | — | — | US | disclosed |
| US-4713387-A | Vasodilating and platelet aggregation inhibiting 1,4 dihydropyridines with an imidazolyl or pyridyl containing ester | TOYAMA CHEMICAL CO., LTD. (JP) | 1987-12-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250034121-A1 | COMPOUNDS AND THEIR USES AS GPR183 INHIBITORS | GPR183, GPR180, GPR65 | AKR1C3 3522/4885MAPT 3530/4885KMT2A 3673/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.