Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CASP1 | P29466 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL766049 | 0.82 | LMNA (0.44) | ACHEGAAALDH1A1LMNAHPGD | |
| Formaldehyde SCHEMBL27840138 | 0.78 | MEN1 (0.42) | ACHEGAAALDH1A1LMNAHPGD | |
| SCHEMBL13594635 | 0.78 | EGFR (0.40) | ALDH1A1LMNAHPGDHSD17B10CYP1A2 | |
| SCHEMBL3070179 | 0.76 | ALDH1A1 (0.45) | ALDH1A1LMNAHPGDHSD17B10CYP1A2 | |
| SCHEMBL2662650 | 0.76 | GAA (0.45) | GAAALDH1A1LMNAHSD17B10CYP1A2 | |
| SCHEMBL6050007 | 0.74 | CYP3A4 (0.50) | GAAALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL10228514 | 0.73 | TRPA1 (0.35) | GAALMNAHTTCYP3A4 | |
| SCHEMBL12878626 | 0.73 | TRPA1 (0.35) | GAALMNAHTTCYP3A4 | |
| SCHEMBL10228517 | 0.73 | ALDH1A1 (0.52) | ACHEGAAALDH1A1LMNAHPGD | |
| SCHEMBL8283598 | 0.73 | CA14 (0.41) | GAAALDH1A1LMNAHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230151014-A1 | COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF PREPARING COMPOUNDS AND OF THEIR USE | REPARE THERAPEUTICS INC. (CA) | 2023-05-18 | — | — | US | disclosed |
| CN-113994258-A | Curable resin composition, cured film, laminate, method for producing cured film, and semiconductor device | 富士胶片株式会社 | 2022-01-28 | — | — | CN | disclosed |
| WO-2021055295-A1 | BRD9 BIFUNCTIONAL DEGRADERS AND THEIR METHODS OF USE | NOVARTIS AG (CH) | 2021-03-25 | — | — | WO | disclosed |
| EP-2448545-B1 | CATALYSED DYE SYSTEMS | UNIV LEEDS (GB) | 2016-09-07 | — | — | EP | disclosed |
| EP-2316413-A2 | Compositions comprising an nfkb-inhibitor and a non-retinoid collagen promoter | Johnson and Johnson Consumer Companies, Inc. (US) | 2011-05-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230151014-A1 | COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF PREPARING COMPOUNDS AND OF THEIR USE | PLK1, CSNK1A1, CSNK1G1 | ACHE 1899/4885GAA 1717/4885ALDH1A1 4093/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.