SCHEMBL126863

SCHEMBL126863

c1ccc2c(c1)cc(-c1c3ccccc3c(-c3cccc4c3oc3ccccc34)c3ccccc13)c1ccccc12

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 3/20 0.50
ALDH1A1 P00352 2/20 0.42
HPGD P15428 2/20 0.42
HSD17B10 Q99714 2/20 0.42
TSHR P16473 1/20 0.42
MAPK1 P28482 1/20 0.42
CASP1 P29466 1/20 0.42
HIF1A Q16665 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
PRKDC P78527 5/20 0.40
PIK3CD O00329 1/20 0.40
PIK3CB P42338 1/20 0.40
GGPS1 O95749 1/20 0.39
ATM Q13315 1/20 0.39
AHR P35869 1/20 0.38
PTGES2 Q9H7Z7 1/20 0.36
KDM4E B2RXH2 1/20 0.36
GAA P10253 1/20 0.36
MAPT P10636 1/20 0.36
SOS1 Q07889 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27329380 0.94 ALOX5 (0.46) ALOX5ALDH1A1HPGDHSD17B10TSHR
SCHEMBL22855199 0.94 ALOX5 (0.48) ALOX5ALDH1A1HPGDHSD17B10TSHR
SCHEMBL22707614 0.93 ALOX5 (0.50) ALOX5ALDH1A1HPGDHSD17B10TSHR
SCHEMBL15195398 0.91 ALOX5 (0.51) ALOX5ALDH1A1HPGDHSD17B10TSHR
SCHEMBL23504642 0.91 ALOX5 (0.49) ALOX5ALDH1A1HPGDHSD17B10TSHR
SCHEMBL13488346 0.89 ALOX5 (0.42) ALOX5ALDH1A1HPGDHSD17B10TSHR
SCHEMBL10122448 0.89 AHR (0.42) ALOX5ALDH1A1HPGDHSD17B10TSHR
SCHEMBL23504641 0.89 ALOX5 (0.50) ALOX5ALDH1A1HPGDHSD17B10TSHR
SCHEMBL12577738 0.89 ALOX5 (0.52) ALOX5ALDH1A1HPGDHSD17B10TSHR
SCHEMBL24090173 0.89 ALOX5 (0.49) ALOX5ALDH1A1HPGDHSD17B10TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 171 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240237533-A1 ORGANIC MOLECULES FOR OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO LTD (KR) 2024-07-11 US disclosed
US-20240228513-A1 ORGANIC MOLECULES FOR OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO LTD (KR) 2024-07-11 US disclosed
US-20240228513-A1 ORGANIC MOLECULES FOR OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO LTD (KR) 2024-07-11 US disclosed
US-20240237533-A1 ORGANIC MOLECULES FOR OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO LTD (KR) 2024-07-11 US disclosed
US-20240224802-A1 ORGANIC MOLECULES FOR OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO LTD (KR) 2024-07-04 US disclosed
US-20240074304-A1 ORGANIC ELECTROLUMINESCENT DEVICE EMITTING BLUE LIGHT SAMSUNG DISPLAY CO., LTD. (KR) 2024-02-29 US disclosed
US-20240032420-A1 ORGANIC ELECTROLUMINESCENT DEVICE EMITTING GREEN LIGHT SAMSUNG DISPLAY CO., LTD. (KR) 2024-01-25 US disclosed
US-20240023436-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2024-01-18 US disclosed
US-11839153-B2 Compound, material for organic electroluminescent element, organic electroluminescent element, and electronic device IDEMITSU KOSAN CO.,LTD. (JP) 2023-12-05 US disclosed
US-20230371364-A1 ORGANIC ELECTROLUMINESCENT DEVICE EMITTING BLUE LIGHT SAMSUNG DISPLAY CO., LTD. (KR) 2023-11-16 US disclosed
US-20120043533-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2012-02-23 US disclosed
US-20110297923-A1 Aromatic amine derivative and organic electroluminescent element using same IDEMITSU KOSAN CO., LTD. 2011-12-08 US disclosed
US-20110297923-A1 Aromatic amine derivative and organic electroluminescent element using same IDEMITSU KOSAN CO., LTD. 2011-12-08 US disclosed
US-20110248217-A1 ELECTROLUMINESCENT DEVICE UDC IRELAND LIMITED (IE) 2011-10-13 US disclosed
US-20110248217-A1 ELECTROLUMINESCENT DEVICE UDC IRELAND LIMITED (IE) 2011-10-13 US disclosed
US-7989644-B2 Electroluminescent device BASF SE (DE) 2011-08-02 US disclosed
US-7989644-B2 Electroluminescent device BASF SE (DE) 2011-08-02 US disclosed
EP-1885818-B1 ELECTROLUMINESCENT DEVICE BASF SE (DE) 2010-01-13 EP disclosed
US-20090131673-A1 Electroluminescent Device UDC IRELAND LIMITED (IE) 2009-05-21 US disclosed
US-20090131673-A1 Electroluminescent Device UDC IRELAND LIMITED (IE) 2009-05-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110248217-A1 ELECTROLUMINESCENT DEVICE DDT, CD99, EED ALOX5 741/4885ALDH1A1 348/4885HPGD 1008/4885
US-20120043533-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING THE SAME AOC2, AOC3, H1-4 ALOX5 3902/4885ALDH1A1 785/4885HPGD 3491/4885
US-11839153-B2 Compound, material for organic electroluminescent element, organic electroluminescent element, and electronic device RER1, RPS19, RPL19 ALOX5 2228/4885ALDH1A1 950/4885HPGD 4093/4885
US-20240023436-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE EED, EML4, ESR1 ALOX5 3824/4885ALDH1A1 1141/4885HPGD 2774/4885
US-20110297923-A1 Aromatic amine derivative and organic electroluminescent element using same H1-4, H1-2, H1-0 ALOX5 4030/4885ALDH1A1 672/4885HPGD 4657/4885
US-20240228513-A1 ORGANIC MOLECULES FOR OPTOELECTRONIC DEVICES OR10J3, ORC3, C1R ALOX5 38/4885ALDH1A1 1539/4885HPGD 3026/4885
US-20240224802-A1 ORGANIC MOLECULES FOR OPTOELECTRONIC DEVICES OR10J3, ORC3, NOX3 ALOX5 1573/4885ALDH1A1 2895/4885HPGD 3238/4885
US-20090131673-A1 Electroluminescent Device DDT, CD99, EED ALOX5 741/4885ALDH1A1 348/4885HPGD 1008/4885
US-20240237533-A1 ORGANIC MOLECULES FOR OPTOELECTRONIC DEVICES OR10J3, C1R, ORC3 ALOX5 182/4885ALDH1A1 1736/4885HPGD 3178/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.