SCHEMBL1268928

SCHEMBL1268928

Cc1ccc(C(N[C@@H](CCCCN)C(=O)O)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 11/20 0.47
MMP2 P08253 1/20 0.46
MMP9 P14780 1/20 0.46
TLR2 O60603 1/20 0.41
FOLH1 Q04609 1/20 0.39
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA9 Q16790 1/20 0.38
ALDH1A1 P00352 1/20 0.38
TSHR P16473 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22634192 0.96 KIF11 (0.48) KIF11MMP2MMP9TLR2
SCHEMBL367485 0.96 KIF11 (0.48) KIF11MMP2MMP9TLR2
SCHEMBL367484 0.96 KIF11 (0.48) KIF11MMP2MMP9TLR2
SCHEMBL29422004 0.92 MMP2 (0.52) KIF11MMP2MMP9TLR2FOLH1
SCHEMBL7593135 0.88 MMP9 (0.47) MMP2MMP9TLR2FOLH1CA1
SCHEMBL17274480 0.86 KIF11 (0.50) KIF11MMP2MMP9TLR2
SCHEMBL7603846 0.86 KIF11 (0.50) KIF11MMP2MMP9TLR2
SCHEMBL25184422 0.85 MMP2 (0.44) KIF11MMP2MMP9TLR2FOLH1
SCHEMBL31453869 0.84 KIF11 (0.52) KIF11MMP2MMP9TLR2
SCHEMBL6137131 0.80 KIF11 (0.47) KIF11CA1CA2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110256532-B RGD cyclopeptide synthesis method 湖北强耀生物科技有限公司 2023-04-14 CN claimed
CN-119504502-A Fmoc-Lys (Mtt) -OH preparation method 四川什邡市三高生化实业有限公司 2025-02-25 CN disclosed
EP-4504342-A1 BIFUNCTIONAL PEPTIDE WITH MUCOADHESIVE AND VIRUS BINDING PROPERTIES Freie Universität Berlin (DE) 2025-02-12 EP disclosed
WO-2023187142-A1 BIFUNCTIONAL PEPTIDE WITH MUCOADHESIVE AND VIRUS BINDING PROPERTIES FREIE UNIVERSITÄT BERLIN (DE) 2023-10-05 WO disclosed
CN-116390938-A Exendin-4 analogues TXP制药股份有限公司 2023-07-04 CN disclosed
EP-4196495-A1 EXENDIN-4 PEPTIDE ANALOGUES TXP Pharma GmbH (CH) 2023-06-21 EP disclosed
CN-110256532-B RGD cyclopeptide synthesis method 湖北强耀生物科技有限公司 2023-04-14 CN disclosed
CN-110256532-B RGD cyclopeptide synthesis method 湖北强耀生物科技有限公司 2023-04-14 CN disclosed
US-20220315631-A1 STAPLED BETA-CATENIN LIGANDS OHIO STATE INNOVATION FOUNDATION 2022-10-06 US disclosed
EP-4021473-A1 STAPLED BETA-CATENIN LIGANDS Ohio State Innovation Foundation (US) 2022-07-06 EP disclosed
WO-2022034062-A1 EXENDIN-4 PEPTIDE ANALOGUES TXP PHARMA AG (CH) 2022-02-17 WO disclosed
WO-2021041895-A1 STAPLED BETA-CATENIN LIGANDS OHIO STATE INNOVATION FOUNDATION (US) 2021-03-04 WO disclosed
WO-2018232491-A1 MITOCHONDRIAL TARGETED RELEASABLE LINKER THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) 2018-12-27 WO disclosed
US-7884183-B2 also targeting tumor cells that express vascular endothelial growth factor neuropilin-1 receptor; radiotherapy; radiopharmaceuticals; treating angiogenesis BRACCO SUISSE SA (CH) 2011-02-08 US disclosed
US-20060263303-A1 Compounds for Targeting Endothelial Cells, Compositions Containing the Same and Methods for Their Use BRACCO INTERNATIONAL BV (NL) 2006-11-23 US disclosed
US-20060258566-A1 Compounds for Targeting Endothelial Cells, Compositions Containing the Same and Methods for Their Use BRACCO INTERNATIONAL BV (NL) 2006-11-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220315631-A1 STAPLED BETA-CATENIN LIGANDS CTNNB1, CTNNBL1, CTNND1 KIF11 3031/4885MMP2 660/4885MMP9 1164/4885
US-20060263303-A1 Compounds for Targeting Endothelial Cells, Compositions Containing the Same and Methods for Their Use VCAM1, FLT1, EDNRA KIF11 1738/4885MMP2 2253/4885MMP9 2225/4885
US-20060258566-A1 Compounds for Targeting Endothelial Cells, Compositions Containing the Same and Methods for Their Use VCAM1, FLT1, EDNRA KIF11 1738/4885MMP2 2253/4885MMP9 2225/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.