SCHEMBL1269356

SCHEMBL1269356

CCCN(CCC)CC1CCc2cc(OCc3ccc(-c4ccccc4)cc3)ccc2C1

nearest known ligand 0.60

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 1/20 0.60
MCHR1 Q99705 3/20 0.52
ITGB3 P05106 1/20 0.47
ITGA2B P08514 1/20 0.47
FFAR1 O14842 1/20 0.45
HRH3 Q9Y5N1 6/20 0.44
CYP2D6 P10635 3/20 0.44
HRH1 P35367 1/20 0.44
DRD2 P14416 4/20 0.44
DRD3 P35462 4/20 0.44
CYP26A1 O43174 1/20 0.43
SIGMAR1 Q99720 1/20 0.42
FAAH O00519 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL4622932 0.99 BACE1 (0.59) BACE1MCHR1ITGB3ITGA2BFFAR1
SCHEMBL1268345 0.87 MCHR1 (0.66) BACE1MCHR1ITGB3ITGA2BFFAR1
Hydrochloric Acid SCHEMBL4622184 0.86 MCHR1 (0.65) BACE1MCHR1ITGB3ITGA2BFFAR1
SCHEMBL361026 0.86 BACE1 (0.65) BACE1MCHR1ITGB3ITGA2BFFAR1
Hydrochloric Acid SCHEMBL4621262 0.85 BACE1 (0.64) BACE1MCHR1ITGB3ITGA2BFFAR1
SCHEMBL1269557 0.83 BACE1 (0.67) BACE1MCHR1ITGB3ITGA2BFFAR1
SCHEMBL361018 0.83 BACE1 (0.67) BACE1MCHR1ITGB3ITGA2BFFAR1
SCHEMBL14440082 0.83 MCHR1 (0.60) BACE1MCHR1ITGB3ITGA2BHRH3
Hydrochloric Acid SCHEMBL4622556 0.82 BACE1 (0.66) BACE1MCHR1ITGB3ITGA2BFFAR1
Water SCHEMBL4978875 0.82 BACE1 (0.66) BACE1MCHR1ITGB3ITGA2BFFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 239 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2305219-A1 Pharmaceutical preparations coated with a copolyvidone-containing coating Takeda Pharmaceutical Company Limited (JP) 2011-04-06 EP claimed
US-20090274733-A1 Pharmaceutical preparation containing copolyvidone TAKEDA PHARMACEUTICAL COMPANY, LTD (JP) 2009-11-05 US claimed
US-20050085553-A1 Remedies for mild recognition deflict TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2005-04-21 US claimed
EP-1459764-A1 REMEDIES FOR MILD RECOGNITION DEFLICT Takeda Chemical Industries, Ltd. (JP) 2004-09-22 EP claimed
US-20040018239-A1 Pharmaceutical preparation containing copolyvidone TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2004-01-29 US claimed
EP-1334732-A1 PHARMACEUTICAL PREPARATION CONTAINING COPOLYVIDONE Takeda Chemical Industries, Ltd. (JP) 2003-08-13 EP claimed
US-20260146047-A1 MACROCYCLIC HETEROCYCLE COMPOUNDS AND USE THEREOF TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2026-05-28 US disclosed
US-12637418-B2 Heterocyclic compounds as antagonist of NMDA TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2026-05-26 US disclosed
CN-122071471-A Heterocyclic compounds 武田药品工业株式会社 2026-05-22 CN disclosed
US-12630534-B2 1-((1H-pyrazol-4-yl)methyl)-3-(phenyl)-1,3-dihydro-2H-imidazol-2-one derivatives and related compounds as GPR139 antagonists for the treatment of e.g. depression TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2026-05-19 US disclosed
CN-122010945-A Heterocyclic compounds 武田药品工业株式会社 2026-05-12 CN disclosed
CN-122010946-A Heterocyclic compounds 武田药品工业株式会社 2026-05-12 CN disclosed
US-20260092033-A1 HETEROCYCLIC COMPOUND AND USE THEREOF TAKEDA PHARMACEUTICALS CO (JP) 2026-04-02 US disclosed
US-20050148650-A1 Antidepressant TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2005-07-07 US disclosed
US-20050085553-A1 Remedies for mild recognition deflict TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2005-04-21 US disclosed
WO-2005032537-A1 METHOD FOR PREVENTING AND/OR TREATING NEURODEGENERATIVE DISEASES ONO PHARMACEUTICAL CO., LTD. (JP) 2005-04-14 WO disclosed
EP-1481679-A1 ANTIDEPRESSANT Takeda Chemical Industries, Ltd. (JP) 2004-12-01 EP disclosed
EP-1459764-A1 REMEDIES FOR MILD RECOGNITION DEFLICT Takeda Chemical Industries, Ltd. (JP) 2004-09-22 EP disclosed
US-20040018239-A1 Pharmaceutical preparation containing copolyvidone TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2004-01-29 US disclosed
EP-1334732-A1 PHARMACEUTICAL PREPARATION CONTAINING COPOLYVIDONE Takeda Chemical Industries, Ltd. (JP) 2003-08-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090274733-A1 Pharmaceutical preparation containing copolyvidone PRCP, COPS6, COPS5 BACE1 4855/4885MCHR1 1553/4885ITGB3 3211/4885
US-20040018239-A1 Pharmaceutical preparation containing copolyvidone PRCP, COPS6, COPS5 BACE1 4855/4885MCHR1 1553/4885ITGB3 3211/4885
US-20050085553-A1 Remedies for mild recognition deflict ACHE, CHAT, PSEN1 BACE1 6/4885MCHR1 1973/4885ITGB3 4360/4885
US-20050148650-A1 Antidepressant AKT1S1, AKT1, AKT2 BACE1 327/4885MCHR1 659/4885ITGB3 3978/4885
US-20260092033-A1 HETEROCYCLIC COMPOUND AND USE THEREOF HCRTR2, HCRTR1, MTNR1B BACE1 350/4885MCHR1 22/4885ITGB3 4668/4885
US-12637418-B2 Heterocyclic compounds as antagonist of NMDA GRIN1, GRIN3A, GRIN2A BACE1 417/4885MCHR1 336/4885ITGB3 1602/4885
US-20260146047-A1 MACROCYCLIC HETEROCYCLE COMPOUNDS AND USE THEREOF HCRTR2, HCRTR1, NPY1R BACE1 1249/4885MCHR1 28/4885ITGB3 3466/4885
US-12630534-B2 1-((1H-pyrazol-4-yl)methyl)-3-(phenyl)-1,3-dihydro-2H-imidazol-2-one derivatives and related compounds as GPR139 antagonists for the treatment of e.g. depression GPR139, OPRL1, GRIN2C BACE1 140/4885MCHR1 464/4885ITGB3 1145/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.