Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.36 |
| ▸ | PCSK9 | Q8NBP7 | 5/20 | 0.35 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.34 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 2/20 | 0.31 |
| ▸ | JAK1 | P23458 | 2/20 | 0.31 |
| ▸ | TYK2 | P29597 | 2/20 | 0.31 |
| ▸ | KDR | P35968 | 2/20 | 0.31 |
| ▸ | JAK3 | P52333 | 2/20 | 0.31 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17082526 | 1.00 | ALDH1A1 (0.56) | ALDH1A1KDM4ESMN1; SMN2ESR1HCAR3 | |
| SCHEMBL15382054 | 0.79 | SMN1; SMN2 (0.59) | ALDH1A1KDM4ESMN1; SMN2HCAR3HCAR2 | |
| SCHEMBL15382066 | 0.79 | SMN1; SMN2 (0.59) | ALDH1A1KDM4ESMN1; SMN2HCAR3HCAR2 | |
| SCHEMBL12693705 | 0.77 | HCAR3 (0.42) | ESR1HCAR3HCRTR1 | |
| SCHEMBL12693737 | 0.76 | HCAR3 (0.41) | ALDH1A1KDM4EESR1HCAR3HCAR2 | |
| SCHEMBL12690881 | 0.75 | ALDH1A1 (0.58) | ALDH1A1KDM4ESMN1; SMN2HCAR3HCAR2 | |
| SCHEMBL21016945 | 0.74 | HCAR3 (0.45) | ALDH1A1SMN1; SMN2ESR1HCAR3HCRTR1 | |
| SCHEMBL17353647 | 0.71 | ALDH1A1 (1.00) | ALDH1A1KDM4ESMN1; SMN2PCSK9MKNK1 | |
| SCHEMBL12693702 | 0.71 | HCAR3 (0.34) | HCAR3HCRTR1 | |
| SCHEMBL19699499 | 0.71 | SMN1; SMN2 (0.45) | ALDH1A1KDM4ESMN1; SMN2HCAR3GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2619196-B1 | OXADIAZOLE INHIBITORS OF LEUKOTRIENE PRODUCTION | BOEHRINGER INGELHEIM INT (DE) | 2015-09-16 | — | — | EP | disclosed |
| US-20120245162-A1 | OXADIAZOLE INHIBITORS OF LEUKOTRIENE PRODUCTION | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-09-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120245162-A1 | OXADIAZOLE INHIBITORS OF LEUKOTRIENE PRODUCTION | LTB4R, LTC4S, LTB4R2 | ALDH1A1 641/4885KDM4E 3731/4885SMN1; SMN2 4210/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.