SCHEMBL12694971

SCHEMBL12694971

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nearest known ligand 0.52

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ FGF1 P05230 7/20 0.52
▸ FGF2 P09038 5/20 0.52
▸ HPSE Q9Y251 14/20 0.40
▸ SERPINC1 P01008 1/20 0.39
▸ F10 P00742 1/20 0.33
▸ VEGFA P15692 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25990456 0.83 SERPINC1 (0.55) FGF1FGF2HPSESERPINC1F10
SCHEMBL4180806 0.83 FGF1 (0.69) FGF1FGF2HPSESERPINC1VEGFA
SCHEMBL12694970 0.78 FGF1 (0.60) FGF1FGF2
SCHEMBL12694972 0.78 FGF1 (0.60) FGF1FGF2
SCHEMBL4906384 0.77 FGF1 (0.70) FGF1FGF2HPSESERPINC1VEGFA
SCHEMBL4904646 0.77 FGF1 (0.70) FGF1FGF2HPSESERPINC1VEGFA
SCHEMBL14020073 0.77 FGF1 (0.70) FGF1FGF2HPSESERPINC1VEGFA
SCHEMBL2524663 0.77 FGF1 (0.62) FGF1FGF2HPSESERPINC1F10
SCHEMBL2528200 0.77 FGF1 (0.62) FGF1FGF2HPSESERPINC1F10
SCHEMBL18742104 0.76 FGF1 (0.76) FGF1FGF2HPSESERPINC1VEGFA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120245120-A1 ZINC SUCROSE OCTASULFATES, THEIR PREPARATION, AND PHARMACEUTICAL AND COSMETIC USES THEREOF PIERRE FABRE DERMO-COSMETIQUE (FR) 2012-09-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120245120-A1 ZINC SUCROSE OCTASULFATES, THEIR PREPARATION, AND PHARMACEUTICAL AND COSMETIC USES THEREOF SLC39A3, SLC39A7, SOD3 FGF1 2532/4885FGF2 2681/4885HPSE 1872/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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