Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | TK1 | P04183 | 7/20 | 0.53 |
| ▸ | POLA1 | P09884 | 1/20 | 0.50 |
| ▸ | POLD1 | P28340 | 1/20 | 0.50 |
| ▸ | NT5M | Q9NPB1 | 1/20 | 0.48 |
| ▸ | DHFR | P00374 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Triphosphate SCHEMBL81707 | 0.95 | POLB (0.55) | POLBTK1POLA1POLD1NT5M | |
| SCHEMBL3154831 | 0.94 | POLB (0.57) | POLBTK1POLA1POLD1NT5M | |
| Phosphoric Acid SCHEMBL3095605 | 0.93 | TK1 (0.52) | TK1DHFR | |
| SCHEMBL9549703 | 0.90 | TK1 (0.50) | POLBTK1DHFR | |
| SCHEMBL78118 | 0.89 | TK1 (0.53) | POLBTK1DHFR | |
| SCHEMBL19242604 | 0.89 | TK1 (0.53) | POLBTK1DHFR | |
| SCHEMBL9549708 | 0.87 | TK1 (0.48) | POLBTK1DHFR | |
| Pyrophosphoric Acid SCHEMBL17541888 | 0.86 | TK1 (0.60) | POLBTK1POLA1POLD1 | |
| Pyrophosphoric Acid SCHEMBL27805609 | 0.86 | TK1 (0.60) | POLBTK1POLA1POLD1 | |
| SCHEMBL9549653 | 0.86 | TK1 (0.50) | POLBTK1DHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10265271-B2 | Microspheres for the treatment of a prostate hyperplasia by active embolization | BIOSPHERE MEDICAL, INC. (US) | 2019-04-23 | — | — | US | disclosed |
| EP-1820495-B1 | Microspheres for active embolization | BIOSPHERE MEDICAL INC (US) | 2017-03-01 | — | — | EP | disclosed |
| US-9308169-B2 | Microspheres for active embolization | BIOSPHERE MEDICAL, INC. (US) | 2016-04-12 | — | — | US | disclosed |
| EP-2286799-B1 | Microspheres for active embolization | BIOSPHERE MEDICAL INC (US) | 2015-07-29 | — | — | EP | disclosed |
| US-8741351-B2 | Microspheres for active embolization | BIOSPHERE MEDICAL, INC. (US) | 2014-06-03 | — | — | US | disclosed |
| US-8697137-B2 | Methods of using microspheres for active embolization | BIOSPHERE MEDICAL, INC. (US) | 2014-04-15 | — | — | US | disclosed |
| US-20120213831-A1 | MICROSPHERES FOR ACTIVE EMBOLIZATION | BIOSPHERE MEDICAL, INC. (US) | 2012-08-23 | — | — | US | disclosed |
| US-20120141379-A1 | MICROSPHERES FOR ACTIVE EMBOLIZATION | BIOSPHERE MEDICAL, INC. (US) | 2012-06-07 | — | — | US | disclosed |
| EP-2286799-A2 | Microspheres for active embolization | BIOSPHERE MEDICAL, INC. (US) | 2011-02-23 | — | — | EP | disclosed |
| US-20080220077-A1 | injectable compositions comprising biocompatible, swellable, substantially hydrophilic, non-toxic and substantially spherical polymeric material carriers which are capable of efficiently delivering bioactive therapeutic factor(s) for use in embolization drug therapy | BIOSPHERE MEDICAL, INC. (US) | 2008-09-11 | — | — | US | disclosed |
| EP-0523189-B1 | CATIONIC LIPIDS FOR INTRACELLULAR DELIVERY OF BIOLOGICALLY ACTIVE MOLECULES | VICAL INC (US) | 1999-06-16 | — | — | EP | disclosed |
| US-5817638-A | USING HYBRID NUCLEOSIDES | NEXSTAR PHARMACEUTICALS, INC. (US) | 1998-10-06 | — | — | US | disclosed |
| EP-0594677-A4 | ANTIVIRAL LIPONUCLEOSIDES: TREATMENT OF HEPATITIS B | VICAL INC (US) | 1997-09-17 | — | — | EP | disclosed |
| US-5459127-A | Drug delivery, extracellular treatment | VICAL, INC. (US) | 1995-10-17 | — | — | US | disclosed |
| EP-0523189-A4 | — | VICAL INC (US) | 1995-04-26 | — | — | EP | disclosed |
| EP-0594677-A1 | ANTIVIRAL LIPONUCLEOSIDES: TREATMENT OF HEPATITIS B | NeXstar Pharmaceuticals, Inc. (US) | 1994-05-04 | — | — | EP | disclosed |
| US-5264618-A | For transport of biological active agents into cells for viral agents or polynucleotides or immunogenic peptides | VICAL, INC. (US) | 1993-11-23 | — | — | US | disclosed |
| WO-1993000910-A1 | ANTIVIRAL LIPONUCLEOSIDES: TREATMENT OF HEPATITIS B | VICAL, INC. (US) | 1993-01-21 | — | — | WO | disclosed |
| EP-0523189-A1 | CATIONIC LIPIDS FOR INTRACELLULAR DELIVERY OF BIOLOGICALLY ACTIVE MOLECULES | VICAL, INC. (US) | 1993-01-20 | — | — | EP | disclosed |
| WO-1991016024-A1 | CATIONIC LIPIDS FOR INTRACELLULAR DELIVERY OF BIOLOGICALLY ACTIVE MOLECULES | VICAL, INC. (US) | 1991-10-31 | — | — | WO | disclosed |