Triphosphate

Triphosphate

SCHEMBL81707

Cc1cn([C@H]2CC[C@@H](C)O2)c(=O)[nH]c1=O.O=P(O)(O)OP(=O)(O)OP(=O)(O)O

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.55
POLA1 P09884 1/20 0.55
POLD1 P28340 1/20 0.55
TK1 P04183 7/20 0.52
NT5M Q9NPB1 1/20 0.46
DHFR P00374 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3154831 0.99 POLB (0.57) POLBPOLA1POLD1TK1NT5M
Pyrophosphoric Acid SCHEMBL1269545 0.95 POLB (0.54) POLBPOLA1POLD1TK1NT5M
Phosphoric Acid SCHEMBL3095605 0.91 TK1 (0.52) TK1DHFR
SCHEMBL9549703 0.88 TK1 (0.50) POLBTK1DHFR
Triphosphate SCHEMBL6066341 0.87 POLB (0.58) POLBPOLA1POLD1TK1
SCHEMBL19242604 0.87 TK1 (0.53) POLBTK1DHFR
SCHEMBL78118 0.87 TK1 (0.53) POLBTK1DHFR
Triphosphate SCHEMBL27892350 0.85 POLB (0.61) POLBPOLA1POLD1TK1
SCHEMBL709680 0.85 POLB (0.57) POLBPOLA1POLD1TK1
SCHEMBL9549708 0.85 TK1 (0.48) POLBTK1DHFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 448 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114144529-B Kit for genotyping 因美纳有限公司 2025-04-29 CN claimed
EP-4253559-B1 KITS FOR GENOTYPING ILLUMINA INC (US) 2025-04-02 EP claimed
EP-4527941-A2 KITS FOR GENOTYPING Illumina, Inc. (US) 2025-03-26 EP claimed
WO-2025042729-A1 CELL PREPARATION COMPOSITION, SYSTEM AND METHOD FOR SINGLE CELL TRANSCRIPTOMICS Life Technologies Corporation (US) 2025-02-27 WO claimed
EP-4479406-A1 OXAZINE DYES AND THEIR USE IN NUCLEIC ACID AMPLIFICATION REACTIONS Promega Corporation (US) 2024-12-25 EP claimed
US-20240287502-A1 OLIGONUCLEOTIDE-TETHERED NUCLEOTIDES THERMO FISHER SCIENTIFIC BALTICS UAB (LT) 2024-08-29 US claimed
US-20240102003-A1 OLIGONUCLEOTIDE-TETHERED NUCLEOTIDES THERMO FISHER SCIENTIFIC BALTICS UAB (LT) 2024-03-28 US claimed
EP-3969613-B1 KITS FOR GENOTYPING ILLUMINA INC (US) 2023-10-04 EP claimed
EP-4253559-A2 KITS FOR GENOTYPING Illumina, Inc. (US) 2023-10-04 EP claimed
US-20230278968-A1 OXAZINE DYES AND THEIR USE IN NUCLEIC ACID AMPLIFICATION REACTIONS PROMEGA CORPORATION 2023-09-07 US claimed
EP-0496749-B1 SPECTRALLY RESOLVABLE RHODAMINE DYES FOR NUCLEIC ACID SEQUENCE DETERMINATION APPLIED BIOSYSTEMS (US) 1995-12-06 EP claimed
EP-0679196-A1 DNA SEQUENCING BY MASS SPECTROMETRY SEQUENOM, INC. (US) 1995-11-02 EP claimed
US-5366860-A Spectrally resolvable rhodamine dyes for nucleic acid sequence determination APPLIED BIOSYSTEMS, INC. (US) 1994-11-22 US claimed
WO-1994016101-A2 DNA SEQUENCING BY MASS SPECTROMETRY KOESTER HUBERT (US) 1994-07-21 WO claimed
EP-0496749-A4 SPECTRALLY RESOLVABLE RHODAMINE DYES FOR NUCLEIC ACID SEQUENCE DETERMINATION 1993-06-16 EP claimed
EP-0496749-A1 SPECTRALLY RESOLVABLE RHODAMINE DYES FOR NUCLEIC ACID SEQUENCE DETERMINATION. APPLIED BIOSYSTEMS (US) 1992-08-05 EP claimed
EP-0286418-B1 ANTI-RETROVIRAL AGENTS AND DELIVERY SYSTEMS FOR THE SAME US COMMERCE (US) 1992-07-08 EP claimed
WO-1991005060-A2 SPECTRALLY RESOLVABLE RHODAMINE DYES FOR NUCLEIC ACID SEQUENCE DETERMINATION APPLIED BIOSYSTEMS, INC. (US) 1991-04-18 WO claimed
WO-1988007854-A1 NEW ANTI-RETROVIRAL AGENTS AND DELIVERY SYSTEM UNITED STATES OF AMERICA, REPRESENTED BY THE UNITE (US) 1988-10-20 WO claimed
EP-0286418-A1 Anti-retroviral agents and delivery systems for the same THE UNITED STATES OF AMERICA as represented by the Secretary United States Department of Commerce (US) 1988-10-12 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230278968-A1 OXAZINE DYES AND THEIR USE IN NUCLEIC ACID AMPLIFICATION REACTIONS POLRMT, POLB, POLN POLB 2/4885POLA1 27/4885POLD1 100/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.