Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | POLA1 | P09884 | 1/20 | 0.57 |
| ▸ | POLD1 | P28340 | 1/20 | 0.57 |
| ▸ | TK1 | P04183 | 7/20 | 0.51 |
| ▸ | DHFR | P00374 | 1/20 | 0.47 |
| ▸ | NT5M | Q9NPB1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Triphosphate SCHEMBL81707 | 0.99 | POLB (0.55) | POLBPOLA1POLD1TK1DHFR | |
| Pyrophosphoric Acid SCHEMBL1269545 | 0.94 | POLB (0.54) | POLBPOLA1POLD1TK1DHFR | |
| Phosphoric Acid SCHEMBL3095605 | 0.90 | TK1 (0.52) | TK1DHFR | |
| SCHEMBL9549703 | 0.87 | TK1 (0.50) | POLBTK1DHFR | |
| Triphosphate SCHEMBL6066341 | 0.86 | POLB (0.58) | POLBPOLA1POLD1TK1 | |
| SCHEMBL19242604 | 0.86 | TK1 (0.53) | POLBTK1DHFR | |
| SCHEMBL78118 | 0.86 | TK1 (0.53) | POLBTK1DHFR | |
| SCHEMBL77582 | 0.85 | POLB (0.68) | POLBPOLA1POLD1TK1 | |
| SCHEMBL265387 | 0.85 | POLB (0.68) | POLBPOLA1POLD1TK1 | |
| SCHEMBL30586988 | 0.85 | POLB (0.68) | POLBPOLA1POLD1TK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546354-B1 | ANALYTE DETECTION | GE HEALTHCARE BIO SCIENCES (US) | 2010-05-05 | — | — | EP | disclosed |
| EP-1427852-B1 | SINGLE NUCLEOTIDE AMPLIFICATION AND DETECTION BY POLYMERASE | GE HEALTHCARE BIO SCIENCES (US) | 2010-02-17 | — | — | EP | disclosed |
| EP-1546354-A4 | ANALYTE DETECTION | GE HEALTHCARE BIO SCIENCES (US) | 2007-08-01 | — | — | EP | disclosed |
| US-7244566-B2 | Detecting one or more biopolymers using terminal phosphate labeled nucleotides; labels employed are enzyme-activatable and include chemiluminescent, fluorescent, electrochemical and chromophoric moieties | GE HEALTHCARE BIO-SCIENCES CORP. (US) | 2007-07-17 | — | — | US | disclosed |
| US-7033762-B2 | Single nucleotide amplification and detection by polymerase | AMERSHAM BIOSCIENCES CORP (US) | 2006-04-25 | — | — | US | disclosed |
| EP-1427852-A4 | SINGLE NUCLEOTIDE AMPLIFICATION AND DETECTION BY POLYMERASE | AMERSHAM BIOSCIENCES CORP (US) | 2005-12-28 | — | — | EP | disclosed |
| EP-1546354-A2 | ANALYTE DETECTION | Amersham Biosciences Corp. (US) | 2005-06-29 | — | — | EP | disclosed |
| US-20040224319-A1 | Analyte detection | GLOBAL LIFE SCIENCES SOLUTIONS USA LLC | 2004-11-11 | — | — | US | disclosed |
| EP-1427852-A2 | SINGLE NUCLEOTIDE AMPLIFICATION AND DETECTION BY POLYMERASE | Amersham Biosciences Corp. (US) | 2004-06-16 | — | — | EP | disclosed |
| WO-2004020603-A2 | ANALYTE DETECTION | AMERSHAM BIOSCIENCES CORP (US) | 2004-03-11 | — | — | WO | disclosed |
| US-20030096253-A1 | Single nucleotide amplification and detection by polymerase | GLOBAL LIFE SCIENCES SOLUTIONS USA LLC | 2003-05-22 | — | — | US | disclosed |
| WO-2003020891-A2 | SINGLE NUCLEOTIDE AMPLIFICATION AND DETECTION BY POLYMERASE | AMERSHAM BIOSCIENCES CORP (US) | 2003-03-13 | — | — | WO | disclosed |