Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 1/20 | 0.37 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.37 |
| ▸ | IDH1 | O75874 | 2/20 | 0.34 |
| ▸ | HTR7 | P34969 | 4/20 | 0.33 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.33 |
| ▸ | BRD7 | Q9NPI1 | 1/20 | 0.33 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12698309 | 0.94 | BRD9 (0.38) | IDH1HTR7BRD9BRD7ALDH1A1 | |
| SCHEMBL8923313 | 0.81 | FNTA (0.40) | IDH1BRD9BRD7CA12CA1 | |
| SCHEMBL16675061 | 0.73 | ALDH1A1 (0.45) | PDCD1CD274HTR7METAP2ALDH1A1 | |
| SCHEMBL5887704 | 0.70 | ALDH1A1 (0.46) | PDCD1CD274METAP2KDM4EALDH1A1 | |
| Benzene SCHEMBL29177892 | 0.70 | ALDH1A1 (0.46) | PDCD1CD274METAP2KDM4EALDH1A1 | |
| SCHEMBL1373278 | 0.69 | ALDH1A1 (0.52) | PDCD1CD274HTR7ALDH1A1TRPA1 | |
| Biphenyl SCHEMBL29177817 | 0.68 | ALDH1A1 (0.45) | PDCD1CD274METAP2KDM4EALDH1A1 | |
| SCHEMBL27414909 | 0.68 | CA12 (0.46) | PDCD1CD274BRD9BRD7CA12 | |
| SCHEMBL26186568 | 0.67 | BRD9 (0.49) | BRD9BRD7METAP2PSMB5ALDH1A1 | |
| SCHEMBL25421508 | 0.66 | ALDH1A1 (0.43) | PDCD1CD274CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9985226-B2 | Triphenylene-based materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2018-05-29 | — | — | US | disclosed |
| US-20130200359-A1 | TRIPHENYLENE-BASED MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2013-08-08 | — | — | US | disclosed |
| US-20130200359-A1 | TRIPHENYLENE-BASED MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2013-08-08 | — | — | US | disclosed |
| WO-2012048781-A1 | TRIPHENYLENE-BASED MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2012-04-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130200359-A1 | TRIPHENYLENE-BASED MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | TERT, TRMT1, TRMT1L | PDCD1 1841/4885CD274 1056/4885IDH1 1233/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.