Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 2/20 | 0.36 |
| ▸ | F2 | P00734 | 3/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | EDNRA | P25101 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10048751 | 0.82 | GAA (0.57) | KDM4EGAAMAPTCA2CYP1A2 | |
| SCHEMBL17807515 | 0.78 | GAA (0.52) | KDM4EGAAMAPTCA2CYP1A2 | |
| SCHEMBL17319458 | 0.76 | MAPT (0.42) | KDM4EGAAMAPTCA2CYP1A2 | |
| SCHEMBL8149846 | 0.75 | CA2 (0.64) | KDM4EGAAMAPTCA2CYP1A2 | |
| SCHEMBL14845761 | 0.75 | GAA (0.61) | KDM4EGAAMAPTCA2CYP1A2 | |
| SCHEMBL4889389 | 0.73 | GAA (0.59) | KDM4EGAAMAPTCA2CYP1A2 | |
| SCHEMBL9676821 | 0.73 | GAA (0.59) | KDM4EGAAMAPTCA2CYP1A2 | |
| SCHEMBL17322787 | 0.73 | GAA (0.59) | KDM4EGAAMAPTCA2CYP1A2 | |
| SCHEMBL30116330 | 0.73 | GAA (0.59) | KDM4EGAAMAPTCA2CYP1A2 | |
| SCHEMBL15631840 | 0.72 | GAA (0.57) | KDM4EGAAMAPTCA2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2502628-A2 | Polynucleotides and polypeptide sequences involved in cancer | Alethia Biotherapeutics Inc. (CA) | 2012-09-26 | — | — | EP | disclosed |