Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 3/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.33 |
| ▸ | EDNRA | P25101 | 4/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12698753 | 0.76 | KDM4E (0.47) | MAPTKDM4EGAACYP1A2CYP2C19 | |
| SCHEMBL10048751 | 0.74 | GAA (0.57) | MAPTKDM4EGAACYP1A2CYP2C19 | |
| SCHEMBL8149846 | 0.71 | CA2 (0.64) | MAPTKDM4EGAACYP1A2CYP2C19 | |
| SCHEMBL14845761 | 0.71 | GAA (0.61) | MAPTKDM4EGAACYP1A2CYP2C19 | |
| SCHEMBL17807515 | 0.71 | GAA (0.52) | MAPTKDM4EGAACYP1A2CYP2C19 | |
| SCHEMBL9676821 | 0.70 | GAA (0.59) | MAPTKDM4EGAACYP1A2CYP2C19 | |
| SCHEMBL4889389 | 0.70 | GAA (0.59) | MAPTKDM4EGAACYP1A2CYP2C19 | |
| SCHEMBL17322787 | 0.70 | GAA (0.59) | MAPTKDM4EGAACYP1A2CYP2C19 | |
| SCHEMBL30116330 | 0.70 | GAA (0.59) | MAPTKDM4EGAACYP1A2CYP2C19 | |
| SCHEMBL10344242 | 0.69 | MAPT (0.49) | MAPTKDM4EGAACYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9205144-B2 | Identification of conserved peptide blocks in homologous polypeptides | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2015-12-08 | — | — | US | disclosed |