SCHEMBL1270085

SCHEMBL1270085

Nc1cccc(OC2(Oc3cccc(N)c3)C=CC(c3ccccc3)=CC2)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 3/20 0.41
MAOA P21397 2/20 0.38
CYP3A4 P08684 2/20 0.36
ALDH1A1 P00352 2/20 0.36
TP53 P04637 1/20 0.33
MAPT P10636 2/20 0.32
POLB P06746 1/20 0.32
HSP90AA1 P07900 1/20 0.32
CYP19A1 P11511 1/20 0.32
ATAD2 Q6PL18 1/20 0.31
MECP2 P51608 1/20 0.31
KDM4E B2RXH2 1/20 0.31
MEN1 O00255 1/20 0.31
LMNA P02545 1/20 0.31
HPGD P15428 1/20 0.31
KMT2A Q03164 1/20 0.31
ATM Q13315 1/20 0.31
PRMT1 Q99873 1/20 0.31
MAP4K4 O95819 2/20 0.30
ASIC3 Q9UHC3 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29720375 1.00 MAOB (0.41) MAOBMAOACYP3A4ALDH1A1TP53
SCHEMBL1119438 0.95 MAOB (0.38) MAOBMAOACYP3A4ALDH1A1TP53
SCHEMBL10382629 0.85
SCHEMBL1119476 0.85 MAOA (0.37) MAOBMAOACYP3A4ALDH1A1MAPT
SCHEMBL713923 0.81 ALOX15 (0.33) CYP3A4ALDH1A1MAPTPOLBHSP90AA1
SCHEMBL8741879 0.80
SCHEMBL8741841 0.80 SLC6A2 (0.34) TSHR
SCHEMBL28110907 0.80 PTGDR2 (0.32) MAOAALDH1A1TP53MAPTPOLB
SCHEMBL30540113 0.79 MGLL (0.49) ALDH1A1MAPTHSP90AA1HPGDKMT2A
SCHEMBL486519 0.79 MGLL (0.49) ALDH1A1MAPTHSP90AA1HPGDKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 133 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9694569-B2 Polyimide metal laminated plate and method of making the same TAIFLEX SCIENTIFIC CO., LTD. (TW) 2017-07-04 US claimed
US-20150367606-A1 POLYIMIDE METAL LAMINATED PLATE AND METHOD OF MAKING THE SAME TAIFLEX SCIENTIFIC CO., LTD. (TW) 2015-12-24 US claimed
US-6919422-B2 Polyimide resin with reduced mold deposit GENERAL ELECTRIC COMPANY (US) 2005-07-19 US claimed
EP-0636661-B1 Polyimide resin composition MITSUI TOATSU CHEMICALS (JP) 1997-11-05 EP claimed
US-5494996-A MELT PROCESSABILITY, HEAT AND AGING RESISTANCE MITSUI TOATSU CHEMICALS INC. (JP) 1996-02-27 US claimed
EP-0636661-A1 Polyimide resin composition MITSUI TOATSU CHEMICALS, Inc. (JP) 1995-02-01 EP claimed
EP-0367482-B1 Polyimides and process for the preparation thereof MITSUI TOATSU CHEMICALS (JP) 1994-09-21 EP claimed
US-5288843-A Polymerizing 4,4'-bis(3-aminophenoxy)biphenyl, pyromellitic dianhydride and a different aromaticdiamine; engineering plastics; molding mateials; aerospace; heat resistance; melt processibility MITSUI TOATSU CHEMICALS, INC. (JP) 1994-02-22 US claimed
EP-0367482-A1 Polyimides and process for the preparation thereof MITSUI TOATSU CHEMICALS, Inc. (JP) 1990-05-09 EP claimed
JP-62205124-A None JP disclosed
JP-4015257-A None JP disclosed
JP-3009747-A None JP disclosed
JP-5059344-A None JP disclosed
JP-6097616-A None JP disclosed
JP-H039747-A INTRAOCULAR LENS STRUCTURE MITSUI TOATSU CHEM INC 1991-01-17 JP disclosed
EP-0387450-A2 Process for making an IC Socket MITSUI TOATSU CHEMICALS, Inc. (JP) 1990-09-19 EP disclosed
US-4847311-A ETHER CONTAINING AMINE, TETRACARBOXYLIC ACID, FIBER REINFORCEMENT MITSUI TOATSU CHEMICALS, INC. (JP) 1989-07-11 US disclosed
EP-0294931-A1 Self-lubricating thermosetting resin composition MITSUI TOATSU CHEMICALS, Inc. (JP) 1988-12-14 EP disclosed
JP-S62205124-A POLYIMIDE MITSUI TOATSU CHEM INC 1987-09-09 JP disclosed
JP-H00415257-A 0001-01-01 JP disclosed