SCHEMBL486519

SCHEMBL486519

O=C1C=CC(=O)N1c1cccc(OC2(Oc3cccc(N4C(=O)C=CC4=O)c3)C=CC(c3ccccc3)=CC2)c1

nearest known ligand 0.49

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 12/20 0.49
FAAH O00519 5/20 0.49
HSP90AA1 P07900 3/20 0.49
ALDH1A1 P00352 3/20 0.49
PKM P14618 2/20 0.49
HTT P42858 2/20 0.49
ATM Q13315 1/20 0.49
HPN P05981 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.34
MAPT P10636 2/20 0.34
MAPK1 P28482 2/20 0.34
HPGD P15428 1/20 0.34
XBP1 P17861 1/20 0.34
CCR6 P51684 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30540113 1.00 MGLL (0.49) MGLLFAAHHSP90AA1ALDH1A1PKM
SCHEMBL8432977 0.88 GRM5 (0.45) MGLLFAAHHSP90AA1ALDH1A1PKM
SCHEMBL486553 0.88 MGLL (0.48) MGLLFAAHHSP90AA1ALDH1A1PKM
SCHEMBL10382629 0.80
SCHEMBL29720375 0.79 MAOB (0.41) HSP90AA1ALDH1A1ATMMAPTHPGD
SCHEMBL1270085 0.79 MAOB (0.41) HSP90AA1ALDH1A1ATMMAPTHPGD
SCHEMBL1119438 0.75 MAOB (0.38) ALDH1A1ATMSMN1; SMN2MAPTHPGD
SCHEMBL9716877 0.73 POLB (0.40) ALDH1A1
SCHEMBL10440247 0.71 LTA4H (0.37)
SCHEMBL1119476 0.71 MAOA (0.37) ALDH1A1SMN1; SMN2MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4968762-A IMPACT STRENGTH, TOUGHNESS, LOW WATER ABSORPTION MITSUI TOATSU CHEMICALS, INC. (JP) 1990-11-06 US claimed
US-20260071011-A1 COMPOUND, RESIN COMPOSITION, PREPREG, RESIN FILM, METAL-CLAD LAMINATE, PRINTED WIRING BOARD, AND SEMICONDUCTOR PACKAGE RESONAC CORP (JP) 2026-03-12 US disclosed
WO-2025105440-A1 CURABLE COMPOSITION, PREPREG, METAL-CLAD LAMINATE, PRINTED WIRING BOARD, SEMICONDUCTOR PACKAGE, AND MOLDED ARTICLE 株式会社レゾナック 2025-05-22 WO disclosed
WO-2025105439-A1 CURABLE COMPOSITION FOR PREPREG, PREPREG, METAL-CLAD LAMINATE, PRINTED WIRING BOARD, AND SEMICONDUCTOR PACKAGE 株式会社レゾナック 2025-05-22 WO disclosed
EP-4527860-A1 RESIN COMPOSITION, PREPREG, LAMINATE, RESIN FILM, PRINTED WIRING BOARD AND SEMICONDUCTOR PACKAGE Resonac Corporation (JP) 2025-03-26 EP disclosed
EP-4488336-A1 RESIN COMPOSITION, PREPREG, LAMINATED BOARD, RESIN FILM, PRINTED WIRING BOARD, AND SEMICONDUCTOR PACKAGE Resonac Corporation (JP) 2025-01-08 EP disclosed
WO-2024257485-A1 COMPOUND, RESIN COMPOSITION, PREPREG, RESIN FILM, METAL-CLAD LAMINATE, PRINTED WIRING BOARD, AND SEMICONDUCTOR PACKAGE 株式会社レゾナック 2024-12-19 WO disclosed
WO-2024214530-A1 RESIN COMPOSITION, PREPREG, RESIN FILM, METAL-CLAD LAMINATE, PRINTED WIRING BOARD, SEMICONDUCTOR PACKAGE, AND ACENAPHTHYLENE HOMOPOLYMER 株式会社レゾナック 2024-10-17 WO disclosed
US-20240279478-A1 RESIN COMPOSITION, RESIN FILM, PRINTED WIRING BOARD, AND SEMICONDUCTOR PACKAGE RESONAC CORPORATION (JP) 2024-08-22 US disclosed
EP-4394000-A1 THERMOSETTING RESIN COMPOSITION AND HEAT CURED PRODUCT Polyplastics-Evonik Corporation (JP) 2024-07-03 EP disclosed
US-8541532-B2 Silane compound, production method thereof, and resin composition containing silane compound NIPPON SHOKUBAI CO., LTD. (JP) 2013-09-24 US disclosed
US-20120247820-A1 RESIN COMPOSITION, PREPREG LAMINATE OBTAINED WITH THE SAME AND PRINTED-WIRING BOARD RESONAC CORPORATION (JP) 2012-10-04 US disclosed
US-20120077401-A1 RESIN COMPOSITION FOR PRODUCTION OF CLAD LAYER, RESIN FILM FOR PRODUCTION OF CLAD LAYER UTILIZING THE RESIN COMPOSITION, AND OPTICAL WAVEGUIDE AND OPTICAL MODULE EACH UTILIZING THE RESIN COMPOSITION OR THE RESIN FILM HITACHI CHEMICAL COMPANY, LTD. (JP) 2012-03-29 US disclosed
EP-2412743-A1 THERMOSETTING RESIN COMPOSITION, AND PREPREG, INSULATING FILM WITH SUPPORT, LAMINATE PLATE, AND PRINTED WIRING BOARD, EACH OBTAINED USING SAME Hitachi Chemical Company, Ltd. (JP) 2012-02-01 EP disclosed
US-20100317774-A1 SILANE COMPOUND, PRODUCTION METHOD THEREOF, AND RESIN COMPOSITION CONTAINING SILANE COMPOUND NIPPON SHOKUBAI CO., LTD (JP) 2010-12-16 US disclosed
US-20080299402-A1 Polyimide film, polyimide metal laminate and process for producing the same MITSUI CHEMICALS, INC. (JP) 2008-12-04 US disclosed
EP-0342943-B1 THERMOSETTING RESIN COMPOSITION MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-08-04 EP disclosed
US-4959443-A HIGH STRENGTH, REACTION OF ARALKYL ALCOHOL AND AROMATIC AMINE MITSUI TOATSU CHEMICALS, INC. (JP) 1990-09-25 US disclosed
EP-0342943-A1 Thermosetting resin composition MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-11-23 EP disclosed
EP-0294931-A1 Self-lubricating thermosetting resin composition MITSUI TOATSU CHEMICALS, Inc. (JP) 1988-12-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100317774-A1 SILANE COMPOUND, PRODUCTION METHOD THEREOF, AND RESIN COMPOSITION CONTAINING SILANE COMPOUND PIEZO1, ORAI2, ARID2 MGLL 4314/4885FAAH 2474/4885HSP90AA1 520/4885
US-20260071011-A1 COMPOUND, RESIN COMPOSITION, PREPREG, RESIN FILM, METAL-CLAD LAMINATE, PRINTED WIRING BOARD, AND SEMICONDUCTOR PACKAGE CD79B, C1R, TGFBR1 MGLL 3867/4885FAAH 4069/4885HSP90AA1 3849/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.