Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10720317 | 0.75 | SERPINE1 (0.31) | SMN1; SMN2POLB | |
| SCHEMBL6681554 | 0.66 | GAA (0.43) | ALDH1A1MEN1KMT2A | |
| SCHEMBL1816515 | 0.66 | ADRA2A (0.48) | — | |
| SCHEMBL821525 | 0.66 | — | — | |
| SCHEMBL5570446 | 0.66 | GSK3A (0.59) | ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL3504167 | 0.64 | DGKA (0.43) | — | |
| SCHEMBL749774 | 0.64 | DGKA (0.54) | ALDH1A1SMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL2353637 | 0.64 | DGKA (0.48) | ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL22360077 | 0.63 | CYP1A2 (0.43) | ALDH1A1SMN1; SMN2KMT2APOLB | |
| SCHEMBL15728324 | 0.63 | NAAA (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8710073-B2 | Anti-infective derivatives, method for the production thereof, pharmaceutical compositions containing same and uses of said derivatives in treatment | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) | 2014-04-29 | — | — | US | disclosed |
| US-20110092536-A1 | NOVEL ANTI-INFECTIOUS DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME AND USES OF SAID DERIVATIVES IN TREATMENT | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFOQUE (C.N. (FR) | 2011-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110092536-A1 | NOVEL ANTI-INFECTIOUS DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME AND USES OF SAID DERIVATIVES IN TREATMENT | DHFR, COASY, QDPR | ALDH1A1 892/4885SMN1; SMN2 4836/4885MEN1 4417/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.