SCHEMBL12705236

SCHEMBL12705236

O=C(OCC12CC3CC(C1)CC(c1ccccc1)(C3)C2)C(F)F

nearest known ligand 0.57

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GRIN2D O15399 1/20 0.46
GRIN3B O60391 1/20 0.46
GRIN1 Q05586 1/20 0.46
GRIN2A Q12879 1/20 0.46
GRIN2B Q13224 1/20 0.46
GRIN2C Q14957 1/20 0.46
GRIN3A Q8TCU5 1/20 0.46
LMNA P02545 5/20 0.46
HSD11B1 P28845 1/20 0.44
ALDH1A1 P00352 2/20 0.44
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
HTT P42858 2/20 0.40
RAD52 P43351 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
GAA P10253 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12705240 0.85 MEN1 (0.45) LMNAALDH1A1MEN1KMT2AHTT
SCHEMBL685724 0.81 LMNA (0.47) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL12705418 0.81 MEN1 (0.49) LMNAHSD11B1ALDH1A1MEN1KMT2A
SCHEMBL12705244 0.80 LMNA (0.46) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL12727402 0.79 LMNA (0.41) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL12705419 0.79 KMT2A (0.47) LMNAHSD11B1ALDH1A1MEN1KMT2A
SCHEMBL1059137 0.79 L3MBTL1 (0.40) LMNAALDH1A1KMT2A
SCHEMBL13483181 0.77 GRIN2D (0.54) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL2948683 0.77 POLB (0.54) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL19149733 0.76 HIF1A (0.46) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110091808-A1 PHOTORESIST COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-04-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110091808-A1 PHOTORESIST COMPOSITION ASIC1, ASIC3, SUN2 GRIN2D 894/4885GRIN3B 1644/4885GRIN1 245/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.