Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.33 |
| ▸ | ALPI | P09923 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11885260 | 1.00 | L3MBTL1 (0.42) | L3MBTL1ALDH1A1KDM4EHTTALOX15 | |
| SCHEMBL1270980 | 1.00 | L3MBTL1 (0.42) | L3MBTL1ALDH1A1KDM4EHTTALOX15 | |
| SCHEMBL21866491 | 0.79 | L3MBTL1 (0.51) | L3MBTL1ALDH1A1KDM4EHTTALOX15 | |
| SCHEMBL21866490 | 0.79 | L3MBTL1 (0.51) | L3MBTL1ALDH1A1KDM4EHTTALOX15 | |
| SCHEMBL14022341 | 0.78 | KDM1A (0.46) | L3MBTL1ALDH1A1KDM4EHTTALOX15 | |
| SCHEMBL10666814 | 0.78 | RECQL (0.42) | L3MBTL1ALDH1A1KDM4EHTTALOX15 | |
| SCHEMBL436495 | 0.78 | ALDH1A1 (0.41) | L3MBTL1ALDH1A1KDM4EALOX15RIPK1 | |
| SCHEMBL469111 | 0.78 | ALDH1A1 (0.41) | L3MBTL1ALDH1A1KDM4EALOX15RIPK1 | |
| SCHEMBL14662457 | 0.78 | KDM1A (0.46) | L3MBTL1ALDH1A1KDM4EHTTALOX15 | |
| SCHEMBL11890232 | 0.78 | UHRF1 (0.45) | L3MBTL1ALDH1A1KDM4EHTTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8227617-B2 | Process for preparing 2-hydroxy-4-substituted pyridines | YUKI GOSEI KOGYO CO., LTD. (JP) | 2012-07-24 | — | — | US | claimed |
| US-20110034697-A1 | PROCESS FOR PREPARING 2-HYDROXY-4-SUBSTITUTED PYRIDINES | YUKI GOSEI KOGYO CO., INC. (JP) | 2011-02-10 | — | — | US | claimed |
| US-20080286843-A1 | Process for Preparing 2-Hydroxy-Substituted Pyridines | YUKI GOSEI KOGYO CO., INC. (JP) | 2008-11-20 | — | — | US | claimed |
| EP-1801102-A1 | PROCESS FOR PRODUCTION OF 2-HYDROXY-4-SUBSTITUTED PYRIDINES | YUKI GOSEI KOGYO CO., LTD. (JP) | 2007-06-27 | — | — | EP | claimed |
| US-8227617-B2 | Process for preparing 2-hydroxy-4-substituted pyridines | YUKI GOSEI KOGYO CO., LTD. (JP) | 2012-07-24 | — | — | US | disclosed |
| US-8227234-B2 | Process for preparing 2-hydroxy-4-substituted pyridines | YUKI GOSEI KOGYO CO., LTD. (JP) | 2012-07-24 | — | — | US | disclosed |
| EP-1801102-B1 | PROCESS FOR PRODUCTION OF 2-HYDROXY-4-SUBSTITUTED PYRIDINES | YUKI GOSEI YAKUHIN KOGYO KK (JP) | 2011-09-07 | — | — | EP | disclosed |
| US-20110034697-A1 | PROCESS FOR PREPARING 2-HYDROXY-4-SUBSTITUTED PYRIDINES | YUKI GOSEI KOGYO CO., INC. (JP) | 2011-02-10 | — | — | US | disclosed |
| US-20110027864-A1 | PROCESS FOR PREPARING 2-HYDROXY-4-SUBSTITUTED PYRIDINES | YUKI GOSEI KOGYO CO., INC. (JP) | 2011-02-03 | — | — | US | disclosed |
| US-7803585-B2 | Process for preparing 2-Hydroxy-4-Substituted Pyridines | YUKI GOSEI KOGYO CO., LTD. (JP) | 2010-09-28 | — | — | US | disclosed |
| US-7803585-B2 | Process for preparing 2-Hydroxy-4-Substituted Pyridines | YUKI GOSEI KOGYO CO., LTD. (JP) | 2010-09-28 | — | — | US | disclosed |
| US-20080286843-A1 | Process for Preparing 2-Hydroxy-Substituted Pyridines | YUKI GOSEI KOGYO CO., INC. (JP) | 2008-11-20 | — | — | US | disclosed |
| US-20080286843-A1 | Process for Preparing 2-Hydroxy-Substituted Pyridines | YUKI GOSEI KOGYO CO., INC. (JP) | 2008-11-20 | — | — | US | disclosed |
| US-20080286843-A1 | Process for Preparing 2-Hydroxy-Substituted Pyridines | YUKI GOSEI KOGYO CO., INC. (JP) | 2008-11-20 | — | — | US | disclosed |
| EP-1801102-A1 | PROCESS FOR PRODUCTION OF 2-HYDROXY-4-SUBSTITUTED PYRIDINES | YUKI GOSEI KOGYO CO., LTD. (JP) | 2007-06-27 | — | — | EP | disclosed |
| EP-1801102-A1 | PROCESS FOR PRODUCTION OF 2-HYDROXY-4-SUBSTITUTED PYRIDINES | YUKI GOSEI KOGYO CO., LTD. (JP) | 2007-06-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080286843-A1 | Process for Preparing 2-Hydroxy-Substituted Pyridines | BPGM, CYP4F11, CYP4F2 | L3MBTL1 2267/4885ALDH1A1 861/4885KDM4E 53/4885 |
| US-20110034697-A1 | PROCESS FOR PREPARING 2-HYDROXY-4-SUBSTITUTED PYRIDINES | HPD, CYP4X1, CYP4B1 | L3MBTL1 4784/4885ALDH1A1 697/4885KDM4E 240/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.