SCHEMBL12715085

SCHEMBL12715085

CCCCCC1C(CC(=O)OC)CCC1OC

nearest known ligand 0.37

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ PTGER2 P43116 4/20 0.35
▸ PRKCA P17252 2/20 0.34
▸ TSHR P16473 1/20 0.34
▸ HTT P42858 1/20 0.34
▸ SMN1; SMN2 Q16637 1/20 0.34
▸ ALOX5 P09917 1/20 0.33
▸ NAAA Q02083 2/20 0.33
▸ POLB P06746 1/20 0.33
▸ POLA1 P09884 1/20 0.33
▸ BRD4 O60885 1/20 0.31
▸ CA12 O43570 1/20 0.31
▸ CA2 P00918 1/20 0.31
▸ CA7 P43166 1/20 0.31
▸ CA9 Q16790 1/20 0.31
▸ CA14 Q9ULX7 1/20 0.31
▸ SPHK1 Q9NYA1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12741978 0.87 PTGER2 (0.39) PTGER2TSHRHTTSMN1; SMN2ALOX5
SCHEMBL12810016 0.87 ALOX5 (0.41) PTGER2TSHRHTTSMN1; SMN2ALOX5
SCHEMBL6916806 0.84 PTGER2 (0.35) PTGER2PRKCATSHRHTTSMN1; SMN2
SCHEMBL2793920 0.84 PTGER2 (0.35) PTGER2PRKCATSHRHTTSMN1; SMN2
SCHEMBL12014043 0.78 BRD4 (0.34) TSHRBRD4
SCHEMBL15526611 0.78 PRKCA (0.34) PTGER2PRKCATSHRHTTSMN1; SMN2
SCHEMBL18019136 0.78 KDM5A (0.36) PTGER2PRKCATSHRHTTSMN1; SMN2
SCHEMBL3938678 0.75 ALOX5 (0.40) PRKCATSHRHTTSMN1; SMN2ALOX5
SCHEMBL3935340 0.75 ALOX5 (0.40) PRKCATSHRHTTSMN1; SMN2ALOX5
SCHEMBL3935336 0.75 ALOX5 (0.40) PRKCATSHRHTTSMN1; SMN2ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8461206-B2 Use of at least one (dihydro)jasmonic acid derivative for treating dry skin L'OREAL (FR) 2013-06-11 — — US disclosed
US-8461206-B2 Use of at least one (dihydro)jasmonic acid derivative for treating dry skin L'OREAL (FR) 2013-06-11 — — US disclosed
US-20110085999-A9 USE OF AT LEAST ONE (DIHYDRO)JASMONIC ACID DERIVATIVE FOR TREATING DRY SKIN L'OREAL S.A. 2011-04-14 — — US disclosed
US-20100015080-A1 USE OF AT LEAST ONE (DIHYDRO)JASMONIC ACID DERIVATIVE FOR TREATING DRY SKIN L'OREAL S.A. 2010-01-21 — — US disclosed
US-7365097-B2 Use of at least one (dihydro)jasmonic acid derivative as a desquamating agent L'OREAL, S.A. (FR) 2008-04-29 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110085999-A9 USE OF AT LEAST ONE (DIHYDRO)JASMONIC ACID DERIVATIVE FOR TREATING DRY SKIN CUTA, ALOX15, ALOX15B PTGER2 104/4885PRKCA 574/4885TSHR 4022/4885
US-20100015080-A1 USE OF AT LEAST ONE (DIHYDRO)JASMONIC ACID DERIVATIVE FOR TREATING DRY SKIN CUTA, ALOX15, ALOX15B PTGER2 104/4885PRKCA 574/4885TSHR 4022/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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