SCHEMBL127154

SCHEMBL127154

Fc1c(F)c(-c2c(F)c(F)c(-c3c(F)c(F)c4c(F)c(F)c(F)c(F)c4c3F)c(F)c2F)c(F)c(F)c1-c1c(F)c(F)c(-c2c(F)c(F)c(-c3c(F)c(F)c4c(F)c(F)c(F)c(F)c4c3F)c(F)c2F)c(F)c1F

nearest known ligand 0.31

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.31
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
TP53 P04637 1/20 0.31
POLB P06746 1/20 0.31
MAPT P10636 1/20 0.31
XBP1 P17861 1/20 0.31
MAPK1 P28482 1/20 0.31
HTT P42858 1/20 0.31
RAB9A P51151 1/20 0.31
HBB P68871 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14948380 1.00 NPC1 (0.31) NPC1ALDH1A1LMNATP53POLB
SCHEMBL5607078 1.00 NPC1 (0.31) NPC1ALDH1A1LMNATP53POLB
SCHEMBL16418950 0.88 NPC1 (0.34) NPC1ALDH1A1LMNATP53POLB
SCHEMBL3397134 0.85
SCHEMBL17676395 0.84
SCHEMBL5943322 0.84
SCHEMBL13798621 0.84
SCHEMBL2726314 0.83 NPC1 (0.36) NPC1ALDH1A1LMNATP53POLB
SCHEMBL3807695 0.83 NPC1 (0.31) NPC1ALDH1A1LMNATP53POLB
SCHEMBL25145272 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1093 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4329431-A2 NOVEL HETEROLEPTIC IRIDIUM COMPLEXES Universal Display Corporation (US) 2024-02-28 EP disclosed
US-11917902-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-02-27 US disclosed
US-11917902-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-02-27 US disclosed
US-20240023424-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-01-18 US disclosed
US-20240023424-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-01-18 US disclosed
US-11832507-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-11-28 US disclosed
US-11832507-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-11-28 US disclosed
EP-3981776-B1 USE OF AN ANCILLARY LIGAND IN A PHOSPHORESCENT METAL COMPLEX COMPOUND UNIVERSAL DISPLAY CORP (US) 2023-11-15 EP disclosed
US-20230337452-A1 PHOSPHORESCENCE-SENSITIZED DELAYED FLUORESCENCE LIGHT EMITTING SYSTEM UNIVERSAL DISPLAY CORPORATION (US) 2023-10-19 US disclosed
US-11793066-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-10-17 US disclosed
US-20100013378-A1 INTERMEDIATE CONNECTOR FOR STACKED ORGANIC LIGHT EMITTING DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2010-01-21 US disclosed
US-20090200927-A1 ORGANIC LIGHT EMITTING DEVICE ARCHITECTURE UNIVERSAL DISPLAY CORPORATION (US) 2009-08-13 US disclosed
US-20090200927-A1 ORGANIC LIGHT EMITTING DEVICE ARCHITECTURE UNIVERSAL DISPLAY CORPORATION (US) 2009-08-13 US disclosed
WO-2009086028-A2 CARBAZOLE-CONTAINING MATERIALS IN PHOSPHORESCENT LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORPORATION (US) 2009-07-09 WO disclosed
US-20090167162-A1 DIBENZOTHIOPHENE-CONTAINING MATERIALS IN PHOSPHORESCENT LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORPORATION (US) 2009-07-02 US disclosed
US-20090167162-A1 DIBENZOTHIOPHENE-CONTAINING MATERIALS IN PHOSPHORESCENT LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORPORATION (US) 2009-07-02 US disclosed
US-20090134784-A1 CARBAZOLE-CONTAINING MATERIALS IN PHOSPHORESCENT LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORPORATION (US) 2009-05-28 US disclosed
US-20090134784-A1 CARBAZOLE-CONTAINING MATERIALS IN PHOSPHORESCENT LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORPORATION (US) 2009-05-28 US disclosed
US-20070181874-A1 Charge transport layers and organic electron devices comprising same E. I. DU PONT DE NEMOURS AND COMPANY 2007-08-09 US disclosed
US-20070181874-A1 Charge transport layers and organic electron devices comprising same E. I. DU PONT DE NEMOURS AND COMPANY 2007-08-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090167162-A1 DIBENZOTHIOPHENE-CONTAINING MATERIALS IN PHOSPHORESCENT LIGHT EMITTING DIODES DDT, BPNT1, DBF4 NPC1 4125/4885ALDH1A1 877/4885LMNA 4528/4885
US-20240023424-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES MLX, LBR, LDLR NPC1 2166/4885ALDH1A1 3581/4885LMNA 201/4885
US-20090134784-A1 CARBAZOLE-CONTAINING MATERIALS IN PHOSPHORESCENT LIGHT EMITTING DIODES OXA1L, PAICS, ORC3 NPC1 2962/4885ALDH1A1 1670/4885LMNA 3596/4885
US-11793066-B2 Organic electroluminescent materials and devices EPCAM, ICMT, ORAI2 NPC1 4197/4885ALDH1A1 3195/4885LMNA 1872/4885
US-11917902-B2 Organic electroluminescent materials and devices SOD1, NDUFV1, L1CAM NPC1 2492/4885ALDH1A1 194/4885LMNA 2195/4885
US-11832507-B2 Organic electroluminescent materials and devices MLX, LBR, LDLR NPC1 2166/4885ALDH1A1 3581/4885LMNA 201/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.