Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.46 |
| ▸ | TK2 | O00142 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.41 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.41 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14855864 | 0.87 | TK1 (0.47) | TK1LMNASMN1; SMN2ADRB1DNMT1 | |
| SCHEMBL1411935 | 0.87 | TK1 (0.47) | TK1LMNASMN1; SMN2ADRB1DNMT1 | |
| SCHEMBL8911352 | 0.79 | ALDH1A1 (0.44) | LMNASMN1; SMN2DNMT1BLMPMP22 | |
| SCHEMBL9780661 | 0.78 | TK1 (0.69) | TK1LMNASMN1; SMN2TK2ALOX12 | |
| SCHEMBL9780646 | 0.78 | TK1 (0.69) | TK1LMNASMN1; SMN2TK2ALOX12 | |
| SCHEMBL6536160 | 0.77 | TK1 (0.45) | TK1LMNASMN1; SMN2ADRB1DNMT1 | |
| SCHEMBL10580076 | 0.77 | TK1 (0.39) | TK1 | |
| SCHEMBL779334 | 0.76 | TK1 (0.42) | TK1LMNASMN1; SMN2ADRB1DNMT1 | |
| SCHEMBL2922542 | 0.76 | TK1 (0.42) | TK1LMNASMN1; SMN2ADRB1DNMT1 | |
| SCHEMBL9092454 | 0.76 | TYMP (0.41) | LMNADNMT1BLMPMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7884202-B2 | Nucleobases are perfluoroalkylated in a one step process with a perfluoroalkyl halide in the presence of a sulfoxide, a peroxide and an iron compound; useful as medicinal drugs, intermediates for medicinal drugs and agricultural chemicals | TOSOH CORPORATION (JP) | 2011-02-08 | — | — | US | disclosed |
| US-20090124796-A1 | Nucleobase Having Perfluoroalkyl Group and Process for Producing the Same | TOSOH CORPORATION (JP) | 2009-05-14 | — | — | US | disclosed |
| US-5703056-A | MONITORING THERAPY | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1997-12-30 | — | — | US | disclosed |
| WO-1996028190-A1 | NON-INVASIVE IMAGING OF GENE TRANSFER | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1996-09-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090124796-A1 | Nucleobase Having Perfluoroalkyl Group and Process for Producing the Same | PFAS, FPGS, NUDT1 | TK1 478/4885LMNA 2811/4885SMN1; SMN2 1728/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.