Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.59 |
| ▸ | RAB9A | P51151 | 6/20 | 0.59 |
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | PKM | P14618 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | CTSA | P10619 | 1/20 | 0.51 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.48 |
| ▸ | MTOR | P42345 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.45 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.44 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12720832 | 0.89 | NPC1 (0.57) | NPC1RAB9AMAPTPKMMEN1 | |
| SCHEMBL12720868 | 0.81 | USP30 (0.48) | NPC1RAB9AMAPTPKMMEN1 | |
| SCHEMBL12720863 | 0.80 | CTSA (0.48) | NPC1RAB9AMAPTPKMMEN1 | |
| SCHEMBL14875861 | 0.78 | CTSA (0.54) | NPC1RAB9AMAPTPKMMEN1 | |
| SCHEMBL18135106 | 0.77 | CTSA (0.56) | NPC1RAB9AMAPTPKMMEN1 | |
| SCHEMBL1053757 | 0.77 | CTSA (0.56) | NPC1RAB9AMAPTPKMMEN1 | |
| SCHEMBL12720802 | 0.76 | AGTR1 (0.71) | NPC1RAB9AMAPTPKMMEN1 | |
| SCHEMBL2465416 | 0.75 | CTSA (0.47) | NPC1RAB9AMAPTPKMMEN1 | |
| SCHEMBL12720811 | 0.74 | AGTR1 (0.58) | NPC1RAB9AMAPTPKMMEN1 | |
| SCHEMBL10098367 | 0.74 | KMO (0.57) | NPC1RAB9AMAPTPKMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7928049-B2 | Use of metal complex compounds as oxidation catalysts | BASF SE Ludwigshafen (DE) | 2011-04-19 | — | — | US | disclosed |
| US-7928049-B2 | Use of metal complex compounds as oxidation catalysts | BASF SE Ludwigshafen (DE) | 2011-04-19 | — | — | US | disclosed |
| US-20110021407-A1 | USE OF METAL COMPLEX COMPOUNDS AS OXIDATION CATALYSTS | CIBA CORPORATION (US) | 2011-01-27 | — | — | US | disclosed |
| US-20110021407-A1 | USE OF METAL COMPLEX COMPOUNDS AS OXIDATION CATALYSTS | CIBA CORPORATION (US) | 2011-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110021407-A1 | USE OF METAL COMPLEX COMPOUNDS AS OXIDATION CATALYSTS | SOD1, MPO, LPO | NPC1 4651/4885RAB9A 4379/4885MAPT 1746/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.