Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12729838 | 0.89 | ALDH1A1 (0.42) | CYP3A4TSHRATMTDP1ALDH1A1 | |
| SCHEMBL7218980 | 0.85 | CYP3A4 (0.64) | CYP3A4TSHRATMTDP1ALDH1A1 | |
| SCHEMBL30019360 | 0.84 | KDM4E (0.56) | CYP3A4TSHRATMTDP1CA2 | |
| SCHEMBL7224114 | 0.82 | CA1 (0.45) | CYP3A4TSHRATMTDP1ALDH1A1 | |
| SCHEMBL12729856 | 0.82 | TSHR (0.44) | CYP3A4TSHRATMTDP1ALDH1A1 | |
| SCHEMBL7629758 | 0.82 | CYP3A4 (0.60) | CYP3A4TSHRATMTDP1ALDH1A1 | |
| SCHEMBL7217028 | 0.82 | CYP3A4 (0.60) | CYP3A4TSHRATMTDP1ALDH1A1 | |
| SCHEMBL23926545 | 0.81 | PRSS1 (0.53) | CYP3A4TSHRATMTDP1ALDH1A1 | |
| SCHEMBL23926544 | 0.81 | PRSS1 (0.53) | CYP3A4TSHRATMTDP1ALDH1A1 | |
| SCHEMBL23926555 | 0.81 | PRSS1 (0.53) | CYP3A4TSHRATMTDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110082210-A1 | FATTY ACID FIBRATE DERIVATIVES AND THEIR USES | CATABASIS PHARMACEUTICALS, INC. | 2011-04-07 | — | — | US | disclosed |
| US-20110082192-A1 | LIPOIC ACID ACYLATED SALICYLATE DERIVATIVES AND THEIR USES | CATABASIS PHARMACEUTICALS, INC. | 2011-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110082210-A1 | FATTY ACID FIBRATE DERIVATIVES AND THEIR USES | FABP1, PPARA, FABP4 | CYP3A4 432/4885TSHR 1281/4885ATM 3415/4885 |
| US-20110082192-A1 | LIPOIC ACID ACYLATED SALICYLATE DERIVATIVES AND THEIR USES | ACACA, ACAT2, ACACB | CYP3A4 2616/4885TSHR 3248/4885ATM 2126/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.