Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PRKCA | P17252 | 1/20 | 0.34 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.34 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.34 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12786987 | 0.89 | TSHR (0.35) | TSHRCYP3A4ATMTDP1ALDH1A1 | |
| SCHEMBL10357895 | 0.83 | PRSS1 (0.47) | TSHRCYP3A4ATMTDP1ALDH1A1 | |
| SCHEMBL12729976 | 0.82 | CYP3A4 (0.46) | TSHRCYP3A4ATMTDP1ALDH1A1 | |
| SCHEMBL12267751 | 0.82 | PRKCA (0.31) | PRKCA | |
| SCHEMBL31325637 | 0.82 | CYP3A4 (0.55) | TSHRCYP3A4ATMTDP1ALDH1A1 | |
| SCHEMBL15443262 | 0.80 | CA2 (0.42) | TSHRCYP3A4ATMTDP1ALDH1A1 | |
| SCHEMBL12267781 | 0.78 | PRKCA (0.31) | PRKCA | |
| SCHEMBL18254442 | 0.78 | TSHR (0.36) | TSHRCYP3A4ATMTDP1ALDH1A1 | |
| SCHEMBL12730613 | 0.78 | — | — | |
| SCHEMBL12267730 | 0.77 | MME (0.33) | TSHRPRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110082210-A1 | FATTY ACID FIBRATE DERIVATIVES AND THEIR USES | CATABASIS PHARMACEUTICALS, INC. | 2011-04-07 | — | — | US | disclosed |
| US-20110082202-A1 | FATTY ACID ACIFRAN DERIVATIVES AND THEIR USES | CATABASIS PHARMACEUTICALS, INC. | 2011-04-07 | — | — | US | disclosed |
| US-20110082120-A1 | SUBSTITUTED THIOACETIC ACID SALICYLATE DERIVATIVES AND THEIR USES | CATABASIS PHARMACEUTICALS, INC. | 2011-04-07 | — | — | US | disclosed |
| US-20110082192-A1 | LIPOIC ACID ACYLATED SALICYLATE DERIVATIVES AND THEIR USES | CATABASIS PHARMACEUTICALS, INC. | 2011-04-07 | — | — | US | disclosed |
| US-20110082156-A1 | FATTY ACID ACIPIMOX DERIVATIVES AND THEIR USES | CATABASIS PHARMACEUTICALS, INC. | 2011-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110082202-A1 | FATTY ACID ACIFRAN DERIVATIVES AND THEIR USES | FABP4, FASN, ELOVL6 | TSHR 1888/4885CYP3A4 1613/4885ATM 2360/4885 |
| US-20110082210-A1 | FATTY ACID FIBRATE DERIVATIVES AND THEIR USES | FABP1, PPARA, FABP4 | TSHR 1281/4885CYP3A4 432/4885ATM 3415/4885 |
| US-20110082120-A1 | SUBSTITUTED THIOACETIC ACID SALICYLATE DERIVATIVES AND THEIR USES | TST, SLC5A2, ACACA | TSHR 752/4885CYP3A4 1407/4885ATM 805/4885 |
| US-20110082192-A1 | LIPOIC ACID ACYLATED SALICYLATE DERIVATIVES AND THEIR USES | ACACA, ACAT2, ACACB | TSHR 3248/4885CYP3A4 2616/4885ATM 2126/4885 |
| US-20110082156-A1 | FATTY ACID ACIPIMOX DERIVATIVES AND THEIR USES | ACOX3, ACOX1, PAOX | TSHR 1559/4885CYP3A4 957/4885ATM 3066/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.