Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NANP | Q8TBE9 | 2/20 | 0.44 |
| ▸ | CD22 | P20273 | 14/20 | 0.39 |
| ▸ | MAG | P20916 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12341443 | 1.00 | NANP (0.44) | NANPCD22MAG | |
| SCHEMBL14454528 | 1.00 | NANP (0.44) | NANPCD22MAG | |
| SCHEMBL15677307 | 0.93 | NANP (0.51) | NANPCD22MAG | |
| SCHEMBL12341462 | 0.92 | NANP (0.47) | NANPCD22MAG | |
| SCHEMBL13477004 | 0.91 | NANP (0.40) | NANPCD22 | |
| SCHEMBL14175641 | 0.91 | NANP (0.40) | NANPCD22 | |
| SCHEMBL12341459 | 0.90 | NANP (0.39) | NANPCD22MAG | |
| SCHEMBL14366095 | 0.90 | NANP (0.44) | NANPCD22MAG | |
| SCHEMBL12991357 | 0.90 | NANP (0.44) | NANPCD22MAG | |
| SCHEMBL14752226 | 0.89 | NANP (0.43) | NANPCD22MAG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9187546-B2 | Compositions and methods for the preparation of protease resistant human growth hormone glycosylation mutants | NOVO NORDISK A/S (DK) | 2015-11-17 | — | — | US | disclosed |
| US-9050304-B2 | Methods of treatment using glycopegylated G-CSF | RATIOPHARM GMBH (DE) | 2015-06-09 | — | — | US | disclosed |
| US-8361961-B2 | O-linked glycosylation of peptides | BIOGENERIX AG (DE) | 2013-01-29 | — | — | US | disclosed |
| US-7932364-B2 | Extended half life; reduced clearance and immunogenicity; industrial scale production; cells, expression cassettes | NOVO NORDISK A/S (DE) | 2011-04-26 | — | — | US | disclosed |
| US-20100120666-A1 | METHODS OF TREATMENT USING GLYCOPEGYLATED G-CSF | BIOGENERIX AG (DE) | 2010-05-13 | — | — | US | disclosed |
| US-20090169509-A1 | O-linked glycosylation of peptides | BIOGENERIX AG (DE) | 2009-07-02 | — | — | US | disclosed |
| US-20090124544-A1 | COMPOSITIONS AND METHODS FOR THE PREPARATION OF PROTEASE RESISTANT HUMAN GROWTH HORMONE GLYCOSYLATION MUTANTS | NEOSE TECHNOLOGIES ,INC. A DELAWARE CORPORATION | 2009-05-14 | — | — | US | disclosed |
| US-20080319183-A1 | Branched Polymeric Sugars and Nucleotides Thereof | NEOSE TECHNOLOGIES, INC. (US) | 2008-12-25 | — | — | US | disclosed |
| US-20080318850-A1 | Glycopegylated Factor Ix | NEOSE TECHNOLOGIES, INC. (US) | 2008-12-25 | — | — | US | disclosed |
| US-20080300173-A1 | Branched Peg Remodeling and Glycosylation of Glucagon-Like Peptides-1 [Glp-1] | NOVO NORDISK A/S (DK) | 2008-12-04 | — | — | US | disclosed |
| US-20080255026-A1 | Glycopegylated Factor Ix | GLYCOPEGYLATED FACTOR 1X | 2008-10-16 | — | — | US | disclosed |
| US-20080242846-A1 | O-LINKED GLYCOSYLATION OF PEPTIDES | NEOSE TECHNOLOGIES, INC. (US) | 2008-10-02 | — | — | US | disclosed |
| US-20080176790-A1 | Remodeling and Glycopegylation of Fibroblast Growth Factor (Fgf) | 89BIO, INC. | 2008-07-24 | — | — | US | disclosed |
| US-20080102083-A1 | Compositions and Methods for the Preparation of Human Growth Hormone Glycosylation Mutants | NEOSE TECHNOLOGIES, INC. (US) | 2008-05-01 | — | — | US | disclosed |
| US-7338933-B2 | Human Growth Hormone polypeptide comprising an O-linked glycosylation site that does not exist in a wild type polypeptide; glycoconjugates in which a species such as a water-soluble polymer, a therapeutic agent or a biomolecule is covalently linked through the site | NEOSE TECHNOLOGIES, INC. (US) | 2008-03-04 | — | — | US | disclosed |
| US-20080015142-A1 | Glycopegylated Follicle Stimulating Hormone | NOVO NORDISK A/S (DK) | 2008-01-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080176790-A1 | Remodeling and Glycopegylation of Fibroblast Growth Factor (Fgf) | FGF2, FGF1, FGFR1 | NANP 163/4885CD22 392/4885MAG 711/4885 |
| US-20080242846-A1 | O-LINKED GLYCOSYLATION OF PEPTIDES | OGA, OGT, OSTC | NANP 343/4885CD22 239/4885MAG 412/4885 |
| US-20080319183-A1 | Branched Polymeric Sugars and Nucleotides Thereof | GALE, NUDT14, GNE | NANP 256/4885CD22 668/4885MAG 1465/4885 |
| US-20080318850-A1 | Glycopegylated Factor Ix | F9, F13A1, F13B | NANP 160/4885CD22 382/4885MAG 212/4885 |
| US-20080255026-A1 | Glycopegylated Factor Ix | F9, F13A1, F13B | NANP 156/4885CD22 390/4885MAG 194/4885 |
| US-20090169509-A1 | O-linked glycosylation of peptides | OGA, OGT, OSTC | NANP 343/4885CD22 239/4885MAG 412/4885 |
| US-20080300173-A1 | Branched Peg Remodeling and Glycosylation of Glucagon-Like Peptides-1 [Glp-1] | GLP1R, GIPR, IAPP | NANP 896/4885CD22 433/4885MAG 736/4885 |
| US-20100120666-A1 | METHODS OF TREATMENT USING GLYCOPEGYLATED G-CSF | CSF3R, CSF1R, SIGLEC7 | NANP 1385/4885CD22 163/4885MAG 375/4885 |
| US-20090124544-A1 | COMPOSITIONS AND METHODS FOR THE PREPARATION OF PROTEASE RESISTANT HUMAN GROWTH HORMONE GLYCOSYLATION MUTANTS | GHITM, PTMS, GHRHR | NANP 386/4885CD22 2233/4885MAG 1324/4885 |
| US-20080102083-A1 | Compositions and Methods for the Preparation of Human Growth Hormone Glycosylation Mutants | GHITM, PTMS, GHRHR | NANP 309/4885CD22 2003/4885MAG 547/4885 |
| US-20080015142-A1 | Glycopegylated Follicle Stimulating Hormone | FSHR, GNRHR, SHBG | NANP 571/4885CD22 592/4885MAG 495/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.