Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.41 |
| ▸ | NPY1R | P25929 | 9/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12733333 | 0.85 | CNR2 (0.40) | KDM4ECNR2MEN1KMT2ATDP1 | |
| SCHEMBL12733324 | 0.80 | CYP2A6 (0.43) | CRHBPCRHR2TSHRKDM4ECNR2 | |
| SCHEMBL12733334 | 0.75 | PKM (0.37) | TSHRKDM4ECNR2MEN1KMT2A | |
| SCHEMBL12733337 | 0.73 | CYP2A6 (0.39) | CNR2MEN1KMT2ATDP1SMN1; SMN2 | |
| SCHEMBL11860620 | 0.72 | LMNA (0.55) | TSHRKDM4EMEN1KMT2ATDP1 | |
| SCHEMBL4547696 | 0.68 | TDP1 (0.44) | TRPM8TSHRMEN1KMT2ATDP1 | |
| SCHEMBL29199898 | 0.63 | ABCG2 (0.56) | KDM4EMEN1KMT2ATDP1MAPT | |
| SCHEMBL7125170 | 0.63 | ABCG2 (0.65) | KDM4EMEN1KMT2ATDP1MAPT | |
| SCHEMBL416349 | 0.62 | TSHR (0.54) | NPY1RTSHRKDM4ETDP1CYP3A4 | |
| SCHEMBL6580997 | 0.61 | ALDH1A1 (0.47) | TSHRMEN1KMT2ATDP1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110098305-A1 | ARYLSULFONAMIDE COMPOUNDS, COMPOSITIONS AND METHODS OF USE | BAELL JONATHAN BAYLDON | 2011-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110098305-A1 | ARYLSULFONAMIDE COMPOUNDS, COMPOSITIONS AND METHODS OF USE | BAX, API5, BCL2 | TRPM8 2627/4885NPY1R 4839/4885HSP90AA1 1304/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.