SCHEMBL1273963

SCHEMBL1273963

c1cc2ccc3sc4ccc5cccc6c(c1)c2c3c4c56

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.61
HSD17B10 Q99714 6/20 0.61
HPGD P15428 4/20 0.61
CYP1A2 P05177 3/20 0.61
THRB P10828 1/20 0.61
ERBB2 P04626 1/20 0.48
FYN P06241 1/20 0.48
MAOA P21397 1/20 0.48
ACHE P22303 1/20 0.48
AHR P35869 1/20 0.48
TSHR P16473 6/20 0.46
CYP3A4 P08684 3/20 0.46
CYP1A1 P04798 1/20 0.46
CYP1B1 Q16678 1/20 0.46
L3MBTL1 Q9Y468 3/20 0.41
TDP1 Q9NUW8 2/20 0.41
GPR3 P46089 1/20 0.40
CYP2A6 P11509 1/20 0.38
CA12 O43570 2/20 0.37
CA9 Q16790 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13935888 0.94 ALDH1A1 (0.54) ALDH1A1HSD17B10HPGDCYP1A2THRB
SCHEMBL13936016 0.94 ALDH1A1 (0.54) ALDH1A1HSD17B10HPGDCYP1A2THRB
SCHEMBL13936008 0.85 HSD17B10 (0.50) ALDH1A1HSD17B10HPGDCYP1A2THRB
SCHEMBL13935884 0.84 HSD17B10 (0.48) ALDH1A1HSD17B10HPGDCYP1A2THRB
SCHEMBL30236746 0.82 ALDH1A1 (0.88) ALDH1A1HSD17B10HPGDCYP1A2THRB
SCHEMBL1293964 0.79 ALDH1A1 (0.56) ALDH1A1HSD17B10HPGDCYP1A2THRB
SCHEMBL30729663 0.79 ALDH1A1 (0.56) ALDH1A1HSD17B10HPGDCYP1A2THRB
SCHEMBL29375094 0.79 ALDH1A1 (0.82) ALDH1A1HSD17B10HPGDCYP1A2THRB
SCHEMBL29370709 0.79 ALDH1A1 (0.82) ALDH1A1HSD17B10HPGDCYP1A2THRB
SCHEMBL606940 0.79 ALDH1A1 (0.82) ALDH1A1HSD17B10HPGDCYP1A2THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11602724-B2 Visible light induced photogeneration of ground state atomic oxygen SAINT LOUIS UNIVERSITY (US) 2023-03-14 US disclosed
US-20220181554-A1 SOLID-STATE IMAGING ELEMENT, METHOD FOR MANUFACTURING SOLID-STATE IMAGING ELEMENT, AND SOLID-STATE IMAGING APPARATUS SONY SEMICONDUCTOR SOLUTIONS CORPORATION (JP) 2022-06-09 US disclosed
US-20200346183-A1 VISIBLE LIGHT INDUCED PHOTOGENERATION OF GROUND STATE ATOMIC OXYGEN SAINT LOUIS UNIVERSITY (US) 2020-11-05 US disclosed
US-20200346183-A1 VISIBLE LIGHT INDUCED PHOTOGENERATION OF GROUND STATE ATOMIC OXYGEN SAINT LOUIS UNIVERSITY (US) 2020-11-05 US disclosed
EP-2464627-B1 PHENANTHRO[1,10,9,8-C,D,E,F,G]CARBAZOLE POLYMERS AND THEIR USE AS ORGANIC SEMICONDUCTORS MERCK PATENT GMBH (DE) 2017-03-01 EP disclosed
US-9455059-B2 Phenanthro [1,10,9,8-c,d,e,f,g]carbazole polymers and their use as organic semiconductors MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2016-09-27 US disclosed
WO-2014098455-A1 NOVEL ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME 주식회사 두산 (KR) 2014-06-26 WO disclosed
EP-2464627-A2 PHENANTHRO[1,10,9,8-C,D,E,F,G]CARBAZOLE POLYMERS AND THEIR USE AS ORGANIC SEMICONDUCTORS Merck Patent GmbH (DE) 2012-06-20 EP disclosed
US-20120138865-A1 PHENANTHROl[1,10,9,8-C,D,E,F,G]CARBAZOLE POLYMERS AND THEIR USE AS ORGANIC SEMICONDUCTORS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2012-06-07 US disclosed
WO-2011018144-A2 PHENANTHRO[1,10,9,8-C,D,E,F,G]CARBAZOLE POLYMERS AND THEIR USE AS ORGANIC SEMICONDUCTORS MERCK PATENT GMBH (DE) 2011-02-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120138865-A1 PHENANTHROl[1,10,9,8-C,D,E,F,G]CARBAZOLE POLYMERS AND THEIR USE AS ORGANIC SEMICONDUCTORS DDT, ESD, DRD3 ALDH1A1 1767/4885HSD17B10 3395/4885HPGD 463/4885
US-20200346183-A1 VISIBLE LIGHT INDUCED PHOTOGENERATION OF GROUND STATE ATOMIC OXYGEN PPOX, SOD1, NFE2L2 ALDH1A1 843/4885HSD17B10 1365/4885HPGD 206/4885
US-11602724-B2 Visible light induced photogeneration of ground state atomic oxygen PPOX, SOD1, NFE2L2 ALDH1A1 843/4885HSD17B10 1365/4885HPGD 206/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.