SCHEMBL12757145

SCHEMBL12757145

Cc1ccc(S(=O)(=O)C(C)(C)C(=O)c2ccc(N(C)c3ccc(C(=O)c4ccc(O)cc4)cc3)cc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.39
ALDH1A1 P00352 2/20 0.39
ELANE P08246 2/20 0.39
MAPT P10636 5/20 0.37
HPGD P15428 2/20 0.37
HTT P42858 2/20 0.37
ESR1 P03372 1/20 0.37
ESR2 Q92731 1/20 0.37
PKM P14618 1/20 0.37
TP53 P04637 2/20 0.36
MCOLN3 Q8TDD5 1/20 0.36
LTC4S Q16873 1/20 0.36
SRD5A2 P31213 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12757143 0.95 LMNA (0.43) LMNAALDH1A1MAPTHPGDTP53
SCHEMBL12757149 0.91 ALDH1A1 (0.47) LMNAALDH1A1MAPTHPGDHTT
SCHEMBL12757141 0.90 NPC1 (0.46) LMNAALDH1A1ELANEHPGDTP53
SCHEMBL12757153 0.89 LMNA (0.38) LMNAALDH1A1MAPTHPGDTP53
SCHEMBL12757144 0.89 KMT2A (0.44) LMNAALDH1A1MAPTHTTTP53
SCHEMBL12757154 0.87 TP53 (0.51) LMNAALDH1A1MAPTTP53SMN1; SMN2
SCHEMBL12757172 0.87 ALOX5 (0.46) ALDH1A1MAPTHPGDHTTLTC4S
SCHEMBL12757151 0.86 ALDH1A1 (0.36) LMNAALDH1A1MAPTHPGDTP53
SCHEMBL12830586 0.86 HCRTR2 (0.43)
SCHEMBL12757127 0.84 ELANE (0.46) LMNAALDH1A1ELANEMAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8342674-B2 Ink composition and inkjet recording method FUJIFILM CORPORATION (JP) 2013-01-01 US disclosed
US-20110074897-A1 INK COMPOSITION AND INKJET RECORDING METHOD FUJIFILM CORPORATION (JP) 2011-03-31 US disclosed