SCHEMBL12757149

SCHEMBL12757149

Cc1ccc(S(=O)(=O)C(C)(C)C(=O)c2ccc(N(C)c3ccc(C(=O)c4ccc(N(C)C)cc4)cc3)cc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.47
MAPT P10636 5/20 0.47
HPGD P15428 2/20 0.47
RAB9A P51151 2/20 0.43
NPC1 O15118 1/20 0.43
PPARG P37231 1/20 0.41
RXFP1 Q9HBX9 1/20 0.41
NR2E3 Q9Y5X4 1/20 0.41
NCOR2 Q9Y618 1/20 0.41
LMNA P02545 2/20 0.41
MAPK1 P28482 1/20 0.41
GFER P55789 1/20 0.41
MCL1 Q07820 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
KDM4E B2RXH2 3/20 0.39
POLB P06746 1/20 0.39
HTT P42858 1/20 0.39
TSHR P16473 1/20 0.38
FLT1 P17948 1/20 0.37
FLT4 P35916 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12757143 0.96 LMNA (0.43) ALDH1A1MAPTHPGDRAB9ANPC1
SCHEMBL12757145 0.91 LMNA (0.39) ALDH1A1MAPTHPGDLMNAHTT
SCHEMBL12757141 0.91 NPC1 (0.46) ALDH1A1HPGDRAB9ANPC1LMNA
SCHEMBL12757144 0.90 KMT2A (0.44) ALDH1A1MAPTLMNATDP1HTT
SCHEMBL12757153 0.90 LMNA (0.38) ALDH1A1MAPTHPGDRAB9ANPC1
SCHEMBL12757121 0.89 ALDH1A1 (0.44) ALDH1A1MAPTHPGDRAB9ANPC1
SCHEMBL12757090 0.89 ALDH1A1 (0.44) ALDH1A1MAPTHPGDRAB9ANPC1
SCHEMBL12757154 0.88 TP53 (0.51) ALDH1A1MAPTLMNAMAPK1MEN1
SCHEMBL12757172 0.88 ALOX5 (0.46) ALDH1A1MAPTHPGDRAB9ANPC1
SCHEMBL12757151 0.87 ALDH1A1 (0.36) ALDH1A1MAPTHPGDRAB9APPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2302007-B1 Ink composition and inkjet recording method FUJIFILM CORP (JP) 2014-01-29 EP disclosed
US-8342674-B2 Ink composition and inkjet recording method FUJIFILM CORPORATION (JP) 2013-01-01 US disclosed
US-8342674-B2 Ink composition and inkjet recording method FUJIFILM CORPORATION (JP) 2013-01-01 US disclosed
US-20110074897-A1 INK COMPOSITION AND INKJET RECORDING METHOD FUJIFILM CORPORATION (JP) 2011-03-31 US disclosed
US-20110074897-A1 INK COMPOSITION AND INKJET RECORDING METHOD FUJIFILM CORPORATION (JP) 2011-03-31 US disclosed