SCHEMBL12757153

SCHEMBL12757153

Cc1ccc(S(=O)(=O)C(C)(C)C(=O)c2ccc(N(C)c3ccc(C(=O)c4ccc(S)cc4)cc3)cc2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.38
ALDH1A1 P00352 2/20 0.38
MAPT P10636 4/20 0.36
TP53 P04637 2/20 0.36
HPGD P15428 2/20 0.36
MCOLN3 Q8TDD5 1/20 0.35
LTC4S Q16873 1/20 0.35
SRD5A2 P31213 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.34
PTPN1 P18031 1/20 0.34
KEAP1 Q14145 1/20 0.33
NFE2L2 Q16236 1/20 0.33
RAB9A P51151 2/20 0.33
PPARG P37231 1/20 0.33
RXFP1 Q9HBX9 1/20 0.33
NR2E3 Q9Y5X4 1/20 0.33
NCOR2 Q9Y618 1/20 0.33
NPC1 O15118 1/20 0.33
MEN1 O00255 1/20 0.32
GAA P10253 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12757143 0.94 LMNA (0.43) LMNAALDH1A1MAPTTP53HPGD
SCHEMBL12757149 0.90 ALDH1A1 (0.47) LMNAALDH1A1MAPTTP53HPGD
SCHEMBL12757145 0.89 LMNA (0.39) LMNAALDH1A1MAPTTP53HPGD
SCHEMBL12757141 0.89 NPC1 (0.46) LMNAALDH1A1TP53HPGDLTC4S
SCHEMBL12757144 0.88 KMT2A (0.44) LMNAALDH1A1MAPTTP53LTC4S
Benzophenone SCHEMBL28397613 0.86 AKR1C3 (0.42) LMNAALDH1A1TP53SRD5A2RAB9A
SCHEMBL12757154 0.86 TP53 (0.51) LMNAALDH1A1MAPTTP53SMN1; SMN2
SCHEMBL12757172 0.86 ALOX5 (0.46) ALDH1A1MAPTHPGDLTC4SRAB9A
SCHEMBL12757151 0.85 ALDH1A1 (0.36) LMNAALDH1A1MAPTTP53HPGD
SCHEMBL12830586 0.85 HCRTR2 (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2302007-B1 Ink composition and inkjet recording method FUJIFILM CORP (JP) 2014-01-29 EP disclosed
US-8342674-B2 Ink composition and inkjet recording method FUJIFILM CORPORATION (JP) 2013-01-01 US disclosed
US-8342674-B2 Ink composition and inkjet recording method FUJIFILM CORPORATION (JP) 2013-01-01 US disclosed
US-20110074897-A1 INK COMPOSITION AND INKJET RECORDING METHOD FUJIFILM CORPORATION (JP) 2011-03-31 US disclosed
US-20110074897-A1 INK COMPOSITION AND INKJET RECORDING METHOD FUJIFILM CORPORATION (JP) 2011-03-31 US disclosed