SCHEMBL1276306

SCHEMBL1276306

c1cc(SCC2CS2)cc(SCC2CS2)c1

nearest known ligand 0.38

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 4/20 0.35
MAOA P21397 1/20 0.33
APEX1 P27695 1/20 0.31
ALDH1A1 P00352 1/20 0.30
MAPK1 P28482 1/20 0.30
LMNA P02545 1/20 0.30
MAPT P10636 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4853977 0.91 CRBN (0.31) CRBN
SCHEMBL4860562 0.88 ALDH1A1 (0.34) CRBNALDH1A1
SCHEMBL19876746 0.87 TMEM97 (0.38) CRBN
SCHEMBL4645061 0.87
SCHEMBL1778553 0.85 ALDH1A1 (0.46) CRBNMAOAALDH1A1MAPK1LMNA
SCHEMBL1276577 0.82 CRBN (0.33) CRBNMAPT
SCHEMBL6600498 0.78 CRBN (0.32) CRBN
SCHEMBL19890915 0.77 MAOA (0.44) CRBNMAOAALDH1A1MAPT
SCHEMBL1402573 0.77 MAPT (0.34) CRBNMAPTKMT2A
SCHEMBL1402747 0.77 NR1H2 (0.32) CRBNMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 152 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2963457-B1 OPTICAL MATERIAL, COMPOSITION FOR USE THEREIN, AND USE THEREOF MITSUI CHEMICALS INC (JP) 2018-07-11 EP claimed
EP-4397693-A1 EPISULFIDE COMPOSITION, POLYMERIZABLE COMPOSITION, CURED PRODUCT, AND OPTICAL MATERIAL Mitsui Chemicals, Inc. (JP) 2024-07-10 EP disclosed
US-20230374191-A1 COMPOSITION, AND OPTICAL MATERIAL AND LENS USING SAME MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2023-11-23 US disclosed
US-20230374191-A1 COMPOSITION, AND OPTICAL MATERIAL AND LENS USING SAME MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2023-11-23 US disclosed
US-20230357507-A1 SULFUR-CONTAINING POLYMER, METHOD FOR PRODUCING SAME, AND SULFUR-CONTAINING POLYMER COMPOSITION NIPPON SHOKUBAI CO., LTD. (JP) 2023-11-09 US disclosed
US-20230339921-A1 COMPOSITION, AND OPTICAL MATERIAL AND LENS USING SAID COMPOSITION MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2023-10-26 US disclosed
US-20230339921-A1 COMPOSITION, AND OPTICAL MATERIAL AND LENS USING SAID COMPOSITION MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2023-10-26 US disclosed
EP-4230616-A1 COMPOSITION, AND OPTICAL MATERIAL AND LENS USING SAID COMPOSITION MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2023-08-23 EP disclosed
EP-4220242-A1 SULFUR-CONTAINING POLYMER, METHOD FOR PRODUCING SAME, AND SULFUR-CONTAINING POLYMER COMPOSITION Nippon Shokubai Co., Ltd. (JP) 2023-08-02 EP disclosed
EP-4206187-A1 COMPOSITION, AND OPTICAL MATERIAL AND LENS USING SAME MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2023-07-05 EP disclosed
US-20030149230-A1 Polythiol compound MITSUI CHEMICALS, INC. (JP) 2003-08-07 US disclosed
US-6596841-B2 For producing resin which is used for optical material such as a plastic lens, a prism, an optical fiber, a substrate for an information recording medium, a filter and a light emitting diodes; refractive index MITSUI CHEMICALS, INC. (JP) 2003-07-22 US disclosed
US-6458917-B2 CURABLE; POLYSULFIDES MITSUI CHEMICALS, INC. (JP) 2002-10-01 US disclosed
US-20020022713-A1 Polythiol, polymerizable composition, resin and lens, and process for preparing thiol compound MITSUI CHEMICALS, INC. (JP) 2002-02-21 US disclosed
US-20020019511-A1 Polymerizable composition MORIJIRI HIROYUKI (JP) 2002-02-14 US disclosed
US-6300464-B2 HIGH HEAT RESISTANCE AND REFRACTIVE INDEX, LOW SPECIFIC GRAVITY; POLYMERS CONTAINING THIO(EPOXY) AND AT LEAST ONE DISULFIDE BOND MITSUI CHEMICAL, INC. (JP) 2001-10-09 US disclosed
EP-1138670-A1 Polythiol, polymerizable composition, resin and lens, and process for preparing thiol compound Mitsui Chemicals, Inc. (JP) 2001-10-04 EP disclosed
US-20010002413-A1 Polymerizable composition MORIJIRI HIROYUKI (JP) 2001-05-31 US disclosed
US-6204311-B1 (THIO)EPOXY COMPOUND HAVING AT LEAST ONE INTRAMOLECULAR DISULFIDE BOND AND A CURING CATALYST. MITSUI CHEMICALS, INC. (JP) 2001-03-20 US disclosed
EP-0942027-A2 A polymerizable composition Mitsui Chemicals, Inc. (JP) 1999-09-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230339921-A1 COMPOSITION, AND OPTICAL MATERIAL AND LENS USING SAID COMPOSITION CRYAA, UACA, CRYZ CRBN 1901/4885MAOA 4284/4885APEX1 1933/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.