Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | USP5 | P45974 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6478473 | 0.93 | ITGB3 (0.50) | ITGB3ITGA2BALDH1A1ALOX15L3MBTL3 | |
| SCHEMBL27298511 | 0.90 | ITGB3 (0.42) | ITGB3ITGA2BALDH1A1ALOX15L3MBTL3 | |
| SCHEMBL2539077 | 0.87 | ITGB3 (0.52) | ITGB3ITGA2BALDH1A1ALOX15SIGMAR1 | |
| SCHEMBL12881317 | 0.84 | ALDH1A1 (0.45) | ALDH1A1ALOX15L3MBTL3L3MBTL1SIGMAR1 | |
| SCHEMBL12881689 | 0.83 | ITGB3 (0.42) | ITGB3ITGA2BALDH1A1ALOX15L3MBTL3 | |
| SCHEMBL7198313 | 0.81 | SIGMAR1 (0.63) | ALDH1A1ALOX15SIGMAR1HSD17B10KDM4E | |
| SCHEMBL24802129 | 0.81 | ALDH1A1 (0.49) | ALDH1A1ALOX15L3MBTL3L3MBTL1SIGMAR1 | |
| SCHEMBL12774006 | 0.81 | SIGMAR1 (0.44) | ALDH1A1L3MBTL3L3MBTL1SIGMAR1ACHE | |
| SCHEMBL27486049 | 0.81 | MEN1 (0.51) | ITGB3ITGA2BALDH1A1ALOX15L3MBTL3 | |
| SCHEMBL9391670 | 0.80 | HSD17B10 (0.52) | ALDH1A1ALOX15SIGMAR1HSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7897603-B2 | Selected CGRP-antagonists, processes for preparing them and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-03-01 | — | — | US | disclosed |
| US-20110034444-A1 | SELECTED CGRP ANTAGONISTS, PROCESSES FOR PREPARING THEM AND THEIR USE AS PHARMACEUTICAL COMPOSITIONS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-02-10 | — | — | US | disclosed |
| WO-2007036532-A2 | SELECTED CGRP ANTAGONISTS, METHODS FOR THE PRODUCTION THEREOF AND THEIR USE AS MEDICAMENTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-04-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110034444-A1 | SELECTED CGRP ANTAGONISTS, PROCESSES FOR PREPARING THEM AND THEIR USE AS PHARMACEUTICAL COMPOSITIONS | CALCRL, CALCR, CALCA | ITGB3 3127/4885ITGA2B 3901/4885ALDH1A1 2010/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.