SCHEMBL12780896

SCHEMBL12780896

c1ccc(-c2ccc(N(c3ccccc3)c3ccc(-c4ccc(N(c5ccccc5)c5ccc(-c6ccc(-c7ccc(-c8ccc(N(c9ccccc9)c9ccc(-c%10ccc(N(c%11ccccc%11)c%11ccc(-c%12ccccc%12)cc%11)cc%10)cc9)cc8)cc7)cc6)cc5)cc4)cc3)cc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 6/20 0.59
▸ TDP1 Q9NUW8 3/20 0.59
▸ L3MBTL1 Q9Y468 2/20 0.59
▸ CYP1A2 P05177 2/20 0.59
▸ CYP3A4 P08684 2/20 0.59
▸ MAPT P10636 2/20 0.59
▸ KDM4E B2RXH2 1/20 0.59
▸ CYP2D6 P10635 1/20 0.59
▸ CYP2C9 P11712 1/20 0.59
▸ CYP2C19 P33261 1/20 0.59
▸ MEN1 O00255 1/20 0.48
▸ CRHBP P24387 1/20 0.48
▸ KMT2A Q03164 1/20 0.48
▸ ATM Q13315 1/20 0.48
▸ CRHR2 Q13324 1/20 0.48
▸ TLR9 Q9NR96 1/20 0.48
▸ CA1 P00915 1/20 0.46
▸ CA2 P00918 1/20 0.46
▸ MGLL Q99685 1/20 0.46
▸ TAAR1 Q96RJ0 3/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14160258 1.00 ALDH1A1 (0.59) ALDH1A1TDP1L3MBTL1CYP1A2CYP3A4
SCHEMBL16305493 1.00 ALDH1A1 (0.59) ALDH1A1TDP1L3MBTL1CYP1A2CYP3A4
SCHEMBL15807420 1.00 ALDH1A1 (0.59) ALDH1A1TDP1L3MBTL1CYP1A2CYP3A4
SCHEMBL24755117 1.00 ALDH1A1 (0.59) ALDH1A1TDP1L3MBTL1CYP1A2CYP3A4
SCHEMBL19593334 1.00 ALDH1A1 (0.59) ALDH1A1TDP1L3MBTL1CYP1A2CYP3A4
SCHEMBL24467954 1.00 ALDH1A1 (0.59) ALDH1A1TDP1L3MBTL1CYP1A2CYP3A4
SCHEMBL12566294 1.00 ALDH1A1 (0.59) ALDH1A1TDP1L3MBTL1CYP1A2CYP3A4
SCHEMBL22017677 1.00 ALDH1A1 (0.59) ALDH1A1TDP1L3MBTL1CYP1A2CYP3A4
SCHEMBL22972387 1.00 ALDH1A1 (0.59) ALDH1A1TDP1L3MBTL1CYP1A2CYP3A4
SCHEMBL805005 1.00 ALDH1A1 (0.59) ALDH1A1TDP1L3MBTL1CYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7902402-B2 N,N'-bis(4-diphenylaminobiphenyl-4'-yl)-N,N'-diphenyl-4,4''-diamino-p-terphenyl; EL element comprises an anode, a hole transport layer, a light emitting layer, an electron transport layer and a cathode laminated sequentially on a substrate; displays; provides high luminance at low applied voltage HODOGAYA CHEMICAL CO., LTD. (JP) 2011-03-08 — — US disclosed
US-7902402-B2 N,N'-bis(4-diphenylaminobiphenyl-4'-yl)-N,N'-diphenyl-4,4''-diamino-p-terphenyl; EL element comprises an anode, a hole transport layer, a light emitting layer, an electron transport layer and a cathode laminated sequentially on a substrate; displays; provides high luminance at low applied voltage HODOGAYA CHEMICAL CO., LTD. (JP) 2011-03-08 — — US disclosed
US-7897816-B2 N,N'-bis(4-diphenylaminobiphenyl-4'-yl)-N,N'-diphenyl-4,4''-diamino-p-terphenyl; EL element comprises an anode, a hole transport layer, a light emitting layer, an electron transport layer and a cathode laminated sequentially on a substrate; displays; provides high luminance at low applied voltage HODOGAYA CHEMICAL CO., LTD. (JP) 2011-03-01 — — US disclosed
US-7897816-B2 N,N'-bis(4-diphenylaminobiphenyl-4'-yl)-N,N'-diphenyl-4,4''-diamino-p-terphenyl; EL element comprises an anode, a hole transport layer, a light emitting layer, an electron transport layer and a cathode laminated sequentially on a substrate; displays; provides high luminance at low applied voltage HODOGAYA CHEMICAL CO., LTD. (JP) 2011-03-01 — — US disclosed
US-7807274-B2 N,N'-bis(4-diphenylaminobiphenyl-4'-yl)-N,N'-diphenyl-4,4''-diamino-p-terphenyl; EL element comprises an anode, a hole transport layer, a light emitting layer, an electron transport layer and a cathode laminated sequentially on a substrate; displays; provides high luminance at low applied voltage HODOGAYA CHEMICAL CO., LTD. (JP) 2010-10-05 — — US disclosed
US-7807274-B2 N,N'-bis(4-diphenylaminobiphenyl-4'-yl)-N,N'-diphenyl-4,4''-diamino-p-terphenyl; EL element comprises an anode, a hole transport layer, a light emitting layer, an electron transport layer and a cathode laminated sequentially on a substrate; displays; provides high luminance at low applied voltage HODOGAYA CHEMICAL CO., LTD. (JP) 2010-10-05 — — US disclosed
US-20100174115-A1 TETRAMINE COMPOUND AND ORGANIC EL DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2010-07-08 — — US disclosed
US-20100174115-A1 TETRAMINE COMPOUND AND ORGANIC EL DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2010-07-08 — — US disclosed
US-20100171080-A1 TETRAMINE COMPOUND AND ORGANIC EL DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2010-07-08 — — US disclosed
US-20100171080-A1 TETRAMINE COMPOUND AND ORGANIC EL DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2010-07-08 — — US disclosed
US-20070149816-A1 N,N'-bis(4-diphenylaminobiphenyl-4'-yl)-N,N'-diphenyl-4,4''-diamino-p-terphenyl; EL element comprises an anode, a hole transport layer, a light emitting layer, an electron transport layer and a cathode laminated sequentially on a substrate; displays; provides high luminance at low applied voltage HODOGAYA CHEMICAL CO., LTD. (JP) 2007-06-28 — — US disclosed
US-20070149816-A1 N,N'-bis(4-diphenylaminobiphenyl-4'-yl)-N,N'-diphenyl-4,4''-diamino-p-terphenyl; EL element comprises an anode, a hole transport layer, a light emitting layer, an electron transport layer and a cathode laminated sequentially on a substrate; displays; provides high luminance at low applied voltage HODOGAYA CHEMICAL CO., LTD. (JP) 2007-06-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070149816-A1 N,N'-bis(4-diphenylaminobiphenyl-4'-yl)-N,N'-diphenyl-4,4''-diamino-p-terphenyl; EL element comprises an anode, a hole transport layer, a light emitting layer, an electron transport layer and a cathode laminated sequentially on a substrate; displays; provides high luminance at low applied voltage SLC6A19, TEAD4, RPL19 ALDH1A1 869/4885TDP1 2104/4885L3MBTL1 285/4885
US-20100171080-A1 TETRAMINE COMPOUND AND ORGANIC EL DEVICE TTI1, ELF3, TERT ALDH1A1 759/4885TDP1 1517/4885L3MBTL1 225/4885
US-20100174115-A1 TETRAMINE COMPOUND AND ORGANIC EL DEVICE TTI1, TERT, RIF1 ALDH1A1 505/4885TDP1 1063/4885L3MBTL1 251/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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