SCHEMBL12784196

SCHEMBL12784196

CCOC(=O)C(CC(C)(CC)CC)C(C)(CC)CC

nearest known ligand 0.35

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MMP8 P22894 1/20 0.35
ALDH1A1 P00352 3/20 0.34
LMNA P02545 1/20 0.33
HSD17B10 Q99714 1/20 0.33
ALOX15 P16050 1/20 0.32
MGAM O43451 1/20 0.32
GAA P10253 1/20 0.32
SI P14410 1/20 0.32
MGAM2 Q2M2H8 1/20 0.32
SOAT1 P35610 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
CPB2 Q96IY4 1/20 0.31
TRPA1 O75762 1/20 0.30
POLB P06746 1/20 0.30
KMT2A Q03164 1/20 0.30
CYP4F2 P78329 2/20 0.30
CYP4A11 Q02928 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14354544 0.85 MMP8 (0.35) MMP8ALDH1A1LMNAHSD17B10ALOX15
SCHEMBL12783174 0.82 ALDH1A1 (0.41) ALDH1A1LMNAL3MBTL1
SCHEMBL22642173 0.80 CYP4F2 (0.38) CYP4F2CYP4A11
SCHEMBL12784233 0.78 HSPD1 (0.33)
SCHEMBL18535321 0.76 CA1 (0.32) LMNAHSD17B10
SCHEMBL14699610 0.73
SCHEMBL22020004 0.73 MMP3 (0.32)
SCHEMBL18630014 0.72
SCHEMBL20018659 0.72
SCHEMBL12524316 0.71 MMP8 (0.36) MMP8ALDH1A1LMNAHSD17B10ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1183048-B1 POLYMERS, COMPOSITIONS AND METHODS OF USE FOR FOAMS, LAUNDRY DETERGENTS, SHOWER RINSES, AND COAGULANTS RHODIA (US) 2011-04-06 EP disclosed
EP-1194461-B1 BLOCK POLYMERS, COMPOSITIONS AND METHODS OF USE FOR FOAMS, LAUNDRY DETERGENTS, SHOWER RINSES AND COAGULANTS RHODIA (US) 2008-10-08 EP disclosed
EP-1180129-B1 LIQUID DETERGENT COMPOSITIONS COMPRISING BLOCK POLYMERIC SUDS ENHANCERS PROCTER & GAMBLE (US) 2007-09-26 EP disclosed