SCHEMBL14354544

SCHEMBL14354544

CCOC(=O)C(CC(C)(C)CC)C(C)(CC)CC

nearest known ligand 0.35

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MMP8 P22894 1/20 0.35
ALDH1A1 P00352 3/20 0.34
LMNA P02545 1/20 0.33
HSD17B10 Q99714 1/20 0.33
ALOX15 P16050 1/20 0.32
MGAM O43451 1/20 0.32
GAA P10253 1/20 0.32
SI P14410 1/20 0.32
MGAM2 Q2M2H8 1/20 0.32
SOAT1 P35610 1/20 0.32
CPB2 Q96IY4 1/20 0.31
TRPA1 O75762 1/20 0.30
CYP4F2 P78329 2/20 0.30
CYP4A11 Q02928 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15259170 0.86 MMP8 (0.36) MMP8ALDH1A1LMNAHSD17B10ALOX15
SCHEMBL13380467 0.85 MMP8 (0.35) MMP8ALDH1A1LMNAHSD17B10ALOX15
SCHEMBL12784196 0.85 MMP8 (0.35) MMP8ALDH1A1LMNAHSD17B10ALOX15
SCHEMBL14641726 0.78 CA2 (0.30)
SCHEMBL14748200 0.76 CA1 (0.32)
SCHEMBL15060853 0.74 LMNA (0.34) MMP8ALDH1A1LMNAHSD17B10ALOX15
SCHEMBL16638380 0.74 GAA (0.35) MMP8ALDH1A1MGAMGAASI
SCHEMBL14641758 0.73
SCHEMBL14365984 0.73 MMP8 (0.39) MMP8ALDH1A1LMNAHSD17B10ALOX15
SCHEMBL14354592 0.73 MMP3 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070287098-A1 MEHTOD FOR PREPARATION OF LITHOGRAPHIC PRINTING PLATE AND LITHOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2007-12-13 US disclosed