Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 4/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.31 |
| ▸ | AXL | P30530 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1654718 | 0.87 | TAS1R3 (0.34) | DYRK1AHSP90AB1AXLKDM4EALDH1A1 | |
| SCHEMBL11918051 | 0.84 | DYRK1A (0.38) | DYRK1AHSP90AB1 | |
| SCHEMBL11903334 | 0.80 | JAK3 (0.38) | ALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL11902200 | 0.79 | MEP1B (0.34) | — | |
| SCHEMBL1654720 | 0.79 | KMO (0.41) | DYRK1AHSP90AB1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL11903110 | 0.78 | ROCK2 (0.31) | KDM4EALDH1A1HSD17B10LIMK1 | |
| SCHEMBL11903222 | 0.76 | SMN1; SMN2 (0.34) | KDM4EALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL11902410 | 0.75 | SMN1; SMN2 (0.34) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL11903387 | 0.75 | DHODH (0.36) | SMN1; SMN2RAB9AHSD17B10 | |
| SCHEMBL11902933 | 0.75 | SMN1; SMN2 (0.34) | KDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011045561-A2 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2011-04-21 | — | — | WO | disclosed |