Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 2/20 | 0.31 |
| ▸ | PRKACA | P17612 | 2/20 | 0.31 |
| ▸ | PRKACG | P22612 | 2/20 | 0.31 |
| ▸ | PRKACB | P22694 | 2/20 | 0.31 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.31 |
| ▸ | LIMK2 | P53671 | 2/20 | 0.31 |
| ▸ | KMO | O15229 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | ALPL | P05186 | 1/20 | 0.30 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1654718 | 0.87 | TAS1R3 (0.34) | KMOKMT2AKDM4EALDH1A1PKM | |
| SCHEMBL11903262 | 0.84 | LIMK1 (0.31) | LIMK1MEN1GAAKMT2AKDM4E | |
| SCHEMBL11913440 | 0.83 | TGFBR1 (0.30) | — | |
| SCHEMBL10252352 | 0.81 | KDM4E (0.35) | MEN1GAAKMT2AKDM4EALDH1A1 | |
| SCHEMBL1655510 | 0.80 | ALPL (0.32) | ROCK2PRKACAPRKACGPRKACBLIMK1 | |
| SCHEMBL11903334 | 0.79 | JAK3 (0.38) | MEN1KMT2AALDH1A1NPSR1HSD17B10 | |
| SCHEMBL11902200 | 0.78 | MEP1B (0.34) | ROCK2KMO | |
| SCHEMBL1654720 | 0.78 | KMO (0.41) | KMOMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL12786369 | 0.78 | DYRK1A (0.34) | LIMK1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL116281 | 0.78 | KDM4E (0.36) | MEN1GAAKMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120202690-A1 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (US) | 2012-08-09 | — | — | US | disclosed |
| US-20120202690-A1 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (US) | 2012-08-09 | — | — | US | disclosed |
| WO-2011045561-A2 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2011-04-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120202690-A1 | HERBICIDAL COMPOUNDS | DDT, HAO2, HAAO | ROCK2 3429/4885PRKACA 1679/4885PRKACG 962/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.