SCHEMBL1278645

SCHEMBL1278645

CC/C(C)=N/NC(=O)c1cc2ccccc2cc1O

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 8/20 0.66
KMT2A Q03164 8/20 0.66
MAPT P10636 8/20 0.66
GAA P10253 8/20 0.66
KDM4E B2RXH2 6/20 0.66
RECQL P46063 4/20 0.66
USP2 O75604 3/20 0.66
CASP6 P55212 1/20 0.66
TDP1 Q9NUW8 4/20 0.62
SMN1; SMN2 Q16637 3/20 0.62
HTT P42858 2/20 0.62
ALDH1A1 P00352 1/20 0.62
GPR39 O43194 1/20 0.61
THRB P10828 4/20 0.61
MPI P34949 1/20 0.61
POLB P06746 6/20 0.60
RAB9A P51151 4/20 0.60
NPC1 O15118 3/20 0.60
PLA2G1B P04054 1/20 0.60
ALOX12 P18054 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6634707 1.00 MEN1 (0.66) MEN1KMT2AMAPTGAAKDM4E
SCHEMBL1278646 1.00 MEN1 (0.66) MEN1KMT2AMAPTGAAKDM4E
SCHEMBL30240801 1.00 MEN1 (0.66) MEN1KMT2AMAPTGAAKDM4E
SCHEMBL1843966 0.89 GAA (0.71) MEN1KMT2AMAPTGAAKDM4E
SCHEMBL6635035 0.89 GAA (0.71) MEN1KMT2AMAPTGAAKDM4E
SCHEMBL30240822 0.89 GAA (0.71) MEN1KMT2AMAPTGAAKDM4E
SCHEMBL2278849 0.89 GAA (0.71) MEN1KMT2AMAPTGAAKDM4E
SCHEMBL1278875 0.85 GPR39 (0.67) MEN1KMT2AMAPTGAAKDM4E
SCHEMBL29587172 0.85 GPR39 (0.67) MEN1KMT2AMAPTGAAKDM4E
SCHEMBL1278351 0.85 MEN1 (0.62) MEN1KMT2AMAPTGAAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250257197-A1 RUBBER COMPOSITION OTSUKA CHEMICAL CO., LTD. (JP) 2025-08-14 US claimed
EP-4509558-A1 RUBBER COMPOSITION Otsuka Chemical Co., Ltd. (JP) 2025-02-19 EP claimed
WO-2023199974-A1 RUBBER COMPOSITION 大塚化学株式会社 2023-10-19 WO claimed
US-20250257197-A1 RUBBER COMPOSITION OTSUKA CHEMICAL CO., LTD. (JP) 2025-08-14 US disclosed
WO-2025100025-A1 TREAD RUBBER COMPOSITION, TREAD RUBBER, AND TIRE 株式会社ブリヂストン 2025-05-15 WO disclosed
WO-2025100279-A1 SIDEWALL RUBBER COMPOSITION AND TIRE 株式会社ブリヂストン 2025-05-15 WO disclosed
EP-4509558-A1 RUBBER COMPOSITION Otsuka Chemical Co., Ltd. (JP) 2025-02-19 EP disclosed
WO-2023199974-A1 RUBBER COMPOSITION 大塚化学株式会社 2023-10-19 WO disclosed
US-11692088-B2 Rubber composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-07-04 US disclosed
US-20230073273-A1 RUBBER COMPOSITION, METHOD FOR PREPARING SAME, AND TIRE FOR CONSTRUCTION VEHICLE THE YOKOHAMA RUBBER CO., LTD. (JP) 2023-03-09 US disclosed
US-20220213295-A1 TRISULFIDE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2022-07-07 US disclosed
EP-1475408-B1 RUBBER COMPOSITION AND PNEUMATIC TIRE MADE THEREFROM BRIDGESTONE CORP (JP) 2011-04-06 EP disclosed
US-20100024937-A1 PNEUMATIC TIRE BRIDGESTONE CORPORATION (JP) 2010-02-04 US disclosed
EP-2116396-A1 PNEUMATIC TIRE Bridgestone Corporation (JP) 2009-11-11 EP disclosed
US-20050176858-A1 Rubber composition and pneumatic tire made therefrom BRIDGESTONE CORPORATION 2005-08-11 US disclosed
EP-1475408-A1 RUBBER COMPOSITION AND PNEUMATIC TIRE MADE THEREFROM Bridgestone Corporation (JP) 2004-11-10 EP disclosed
EP-1199331-B1 Polymaleimide-containing rubber composition and tire BRIDGESTONE CORP (JP) 2004-03-17 EP disclosed
US-6566449-B2 Obtained from polymerized maleic acid and citraconic acid with methylene polyaniline; elasticity; performance BRIDGESTONE CORPORATION (JP) 2003-05-20 US disclosed
US-20020077423-A1 Polymaleimide-containing rubber composition and tire BRIDGESTONE CORPORATION 2002-06-20 US disclosed
EP-1199331-A1 Polymaleimide-containing rubber composition and tire BRIDGESTONE CORPORATION (JP) 2002-04-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220213295-A1 TRISULFIDE COMPOUND TST, TMT1A, SULT1A1 MEN1 4211/4885KMT2A 1220/4885MAPT 4580/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.